Compile Data Set for Download or QSAR
Found 280 with Last Name = 'giorgini' and Initial = 'ml'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329915(1-methyl-8-(5-(piperazin-1-yl)-2-(trifluoromethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329914(1-methyl-8-(5-(4-methylpiperazin-1-yl)-2-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329913(1-(2-fluoroethyl)-8-(5-(piperazin-1-yl)-2-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329926(8-(5-(piperazin-1-yl)-2-(trifluoromethoxy)phenylam...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12103(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 11 | 4-te...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QKKPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327930(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329927(1-ethyl-8-(5-(piperazin-1-yl)-2-(trifluoromethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327929(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12983(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329929(8-(5-(piperazin-1-yl)-2-(trifluoromethoxy)phenylam...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329916(1-(2-chloroethyl)-8-(5-(piperazin-1-yl)-2-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329921(8-(5-(4-ethylpiperazin-1-yl)-2-(trifluoromethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12982(5-Amido-pyrrolopyrazole 9a | CHEMBL385266 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327928(3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMI...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327927(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327915(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579781(CHEMBL5094847)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579779(CHEMBL5091519)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329928(1-(2-methoxyethyl)-8-(5-(piperazin-1-yl)-2-(triflu...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327926(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579773(CHEMBL5079663)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579782(CHEMBL5078600)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579777(CHEMBL5090932)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579771(CHEMBL5077194)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579769(CHEMBL5075042)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12984(4-(4-methylpiperazin-1-yl)-N-{5-[(2R)-2-phenylprop...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329923(1-methyl-8-(5-(4-methyl-1,4-diazepan-1-yl)-2-(trif...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327925(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327924(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12110(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 18 | 5-N-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3QKKPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12110(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 18 | 5-N-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579780(CHEMBL5089356)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579757(CHEMBL5084844)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579775(CHEMBL5085262)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579770(CHEMBL5090132)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579774(CHEMBL5081222)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579785(CHEMBL5075110)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579786(CHEMBL5093152)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM50327922(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329932(1-methyl-8-(2-(trifluoromethoxy)phenylamino)-4,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Nerviano Medical Sciences srl

Curated by ChEMBL
LigandPNGBDBM50329924(1-methyl-8-(5-(4-(pyrrolidin-1-yl)piperidin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1T39PubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579772(CHEMBL5088776)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetCholine kinase alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50579784(CHEMBL5091201)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of ChoKalpha (unknown origin) by HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PFFPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
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