Compile Data Set for Download or QSAR
Found 70 with Last Name = 'yip' and Initial = 'ml'
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24550(3-{2-[(3Z)-5-{[(3-chloro-4-fluorophenyl)methyl]sul...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24538((3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center

LigandPNGBDBM31272(NSC 333003 | NSC-333003)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:When two proteins interact (one of which is conjugated to the donor bead and the other to the acceptor bead) the beads are brought into close proximi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC8XC4PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.24E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 3.71E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
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