Compile Data Set for Download or QSAR
Found 374 with Last Name = 'rayner' and Initial = 'mm'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50214385(CHEMBL316681)copy SMILEScopy InChI
Affinity DataKi: <0.0100nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM162(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-{[3...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM177((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM160(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-{[3...)copy SMILEScopy InChI
Affinity DataKi:  0.0140nM ΔG°:  -64.4kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069201((4R,5S,6S,7R)-5,6-Dihydroxy-4,7-bis-(4-hydroxy-ben...)copy SMILEScopy InChI
Affinity DataKi:  0.0160nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM161((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(1...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM161((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(1...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nM ΔG°:  -63.8kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM1081((4R,5R,6R)-Tetrahydro-1,3-bis[(3-benzamide oxime)m...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nM ΔG°:  -63.8kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RHBPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM178((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nM ΔG°:  -63.8kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288430((4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM155(CHEMBL11266 | N-(1H-1,3-benzodiazol-2-yl)-3-{[(4R,...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nM ΔG°:  -63.5kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM164((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(1H-indazol-5...)copy SMILEScopy InChI
Affinity DataKi:  0.0230nM ΔG°:  -63.2kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM182((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0270nM ΔG°:  -62.8kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM182((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0270nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM154(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-2-oxo...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nM ΔG°:  -62.5kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM180((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0310nM ΔG°:  -62.4kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM179((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0310nM ΔG°:  -62.4kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM175((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0370nM ΔG°:  -61.9kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM156(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-3-[(3-carbamoylphen...)copy SMILEScopy InChI
Affinity DataKi:  0.0390nM ΔG°:  -61.8kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM7031((4R,5S,6S,7R)-4,7-bis(2H-1,3-benzodioxol-5-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  0.0430nM ΔG°:  -61.6kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q257197TPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM159(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-2-oxo...)copy SMILEScopy InChI
Affinity DataKi:  0.0430nM ΔG°:  -61.6kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM168((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-[(3-hyd...)copy SMILEScopy InChI
Affinity DataKi:  0.0450nM ΔG°:  -61.4kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM167(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(1H...)copy SMILEScopy InChI
Affinity DataKi:  0.0490nM ΔG°:  -61.2kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM169((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-{[3-(2-...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nM ΔG°:  -61.2kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM187((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0520nM ΔG°:  -61.1kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50289438((4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1-(3-hydr...)copy SMILEScopy InChI
Affinity DataKi:  0.0580nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M7B
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069199((4R,5S,6S,7R)-5,6-Dihydroxy-4,7-bis-[4-(2-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  0.0590nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069204((4R,5S,6S,7R)-5,6-Dihydroxy-1,3-bis-[3-(1H-pyrazol...)copy SMILEScopy InChI
Affinity DataKi:  0.0590nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM172((4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis[(3-acetylphenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nM ΔG°:  -60.7kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069197((4R,5S,6S,7R)-4,7-Bis-[4-(2-dimethylamino-ethoxy)-...)copy SMILEScopy InChI
Affinity DataKi:  0.0610nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM157(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-{[3...)copy SMILEScopy InChI
Affinity DataKi:  0.0660nM ΔG°:  -60.4kJ/molepH: 5.5 T: 2°CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069196((4R,5S,6S,7R)-5,6-Dihydroxy-1,3-bis-[3-(1H-pyrazol...)copy SMILEScopy InChI
Affinity DataKi:  0.0710nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069203((4R,5S,6S,7R)-5,6-Dihydroxy-4,7-bis-(4-methoxy-ben...)copy SMILEScopy InChI
Affinity DataKi:  0.0780nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM7034((4R,5S,6S,7R)-1,3-bis[(3-acetylphenyl)methyl]-5,6-...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q257197TPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50289443((4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1-(3-hydr...)copy SMILEScopy InChI
Affinity DataKi:  0.0810nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M7B
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM1080((4R,5R,6R)-Tetrahydro-1,3-bis[(3-benzamido)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.0880nM ΔG°:  -59.7kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RHBPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288424((4R,5S,6S,7R)-1,3-Bis-(1H-benzotriazol-5-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50289441((4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1-(4-hydr...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0M7B
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM170(CHEMBL309557 | Cyclic Urea | [4R-(4,5,6,7)]-Methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.110nM ΔG°:  -59.1kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM1726((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[(...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K935QMPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM1727((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[(...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K935QMPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50069206((4R,5S,6S,7R)-5,6-Dihydroxy-4,7-bis-[4-(2-morpholi...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TMPPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288420(5-[4,7-dibenzyl-5,6-dihydroxy-2-oxo-3-(2-oxo-2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM1730((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K935QMPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM184((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.160nM ΔG°:  -58.2kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM186((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.170nM ΔG°:  -58.0kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288421(6-[4,7-dibenzyl-5,6-dihydroxy-2-oxo-3-(2-oxo-2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288434((4R,5S,6S,7R)-4,7-Dibenzyl-1,3-bis-(2,2-dioxo-2,3-...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
DuPont Merck Pharmaceutical Company

LigandPNGBDBM185((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.190nM ΔG°:  -57.7kJ/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1J3MPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288431((4R,5S,6S,7R)-1,3-Bis-(2-amino-benzooxazol-6-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SVC
Displayed 1 to 50 (of 374 total ) | Next | Last >>
Jump to: