Compile Data Set for Download or QSAR
Found 22 with Last Name = 'edelstein' and Initial = 'mp'
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016658(2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016660(2-{4-[2-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016662(2-{4-[3-(2-Amino-4-oxo-3,4,7,8-tetrahydro-pteridin...)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016659(2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of the GAR transformylase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016658(2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0.0140nMAssay Description:Inhibition of the GAR transformylase in MOLT-4 human leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016658(2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of the GAR transformylase in L1210More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016660(2-{4-[2-(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pteri...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of the GAR transformylase in L1210More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against hog liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50014844(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) from L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016661(2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the GAR formyl transferase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016657(2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of the GAR formyl transferase in lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016657(2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-pteridin-6-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of the GAR formyl transferase in L1210More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K27J9PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014844(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase from hog liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 5.74E+5nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HS0PubMed