Compile Data Set for Download or QSAR
Found 278 with Last Name = 'ghadiri' and Initial = 'mr'
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388925(CHEMBL2063396)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Competitive inhibition of HDAC2 using Ac-Lys(Ac)-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
LigandPNGBDBM50388925(CHEMBL2063396)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Competitive inhibition of HDAC3/NCoR2 using Ac-Lys(Ac)-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388926(CHEMBL2063395)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Competitive inhibition of HDAC1 using Ac-Lys(Ac)-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388925(CHEMBL2063396)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Competitive inhibition of HDAC1 using Ac-Lys(Ac)-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant HDAC1 using Ac-Lys(Ac)-AMC as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant HDAC2 using Ac-Lys(Ac)-AMC as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HDAC3/NCoR2 using Ac-Lys(Ac)-AMC as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379130(CHEMBL2012817)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379130(CHEMBL2012817)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379131(CHEMBL2012815)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379131(CHEMBL2012815)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302059(6-((2S,5S,8S,11S)-2-(5-acetamidopentyl)-11-isobuty...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
LigandPNGBDBM50379130(CHEMBL2012817)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM50379130(CHEMBL2012817)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Lys(Ac)-7-amino-4-methylcoumarin as substrate after 30 mins by trypsin-coupled fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32R4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant HDAC3/NCoR2 using Ac-Lys(Ac)-7-amino-4-methylcoumarin as substrate after 30 mins by trypsin-coupled fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32R4PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379129(CHEMBL2012814)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
LigandPNGBDBM50379135(CHEMBL2012818)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human HDAC6 using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant HDAC6 using Ac-Lys(Ac)-AMC as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ122XPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302053((3S,6R,9S,13S)-3-((1H-indol-3-yl)methyl)-13-isobut...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302053((3S,6R,9S,13S)-3-((1H-indol-3-yl)methyl)-13-isobut...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379135(CHEMBL2012818)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302077((3S,6S,9S,13S)-3-((1H-indol-3-yl)methyl)-13-isobut...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50302077((3S,6S,9S,13S)-3-((1H-indol-3-yl)methyl)-13-isobut...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32238PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant HDAC3 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046DKPubMed
LigandPNGBDBM50379132(CHEMBL2012813)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC3/NCoR2 using Ac-Lys(Ac)-7-amino-4-methylcoumarin as substrate after 30 mins by trypsin-coupled fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32R4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50379132(CHEMBL2012813)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Lys(Ac)-7-amino-4-methylcoumarin as substrate after 30 mins by trypsin-coupled fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32R4PubMed
LigandPNGBDBM50302073(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-2-benz...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50302052(6-((2S,5S,8S,11S)-8-((1H-indol-3-yl)methyl)-11-iso...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZRXPubMed
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