Compile Data Set for Download or QSAR
Found 28 with Last Name = 'dupriest' and Initial = 'mt'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010282(2,7-difluorospiro[9H-fluorene-9,3'-(tetrahydro-1'H...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Aldose reductase from rat lensMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010283(2,7-difluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010283(2,7-difluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010282(2,7-difluorospiro[9H-fluorene-9,3'-(tetrahydro-1'H...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010281(2,7-Difluorospiro[9H-fluorene-9,5'-isothiazolidin]...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010281(2,7-Difluorospiro[9H-fluorene-9,5'-isothiazolidin]...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010286(2-Chlorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010276(2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010276(2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 169nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010286(2-Chlorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010278(CHEMBL325136 | Spiro[9H-fluorene-9,5'-isothiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010278(CHEMBL325136 | Spiro[9H-fluorene-9,5'-isothiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010280(2-Fluorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50009777((ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010285(2-Chlorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010284(2,7-DiFluorospiro[9H-fluorene-9,4'-isothiazolidin]...)copy SMILEScopy InChI
Affinity DataIC50: 3.75E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010277(CHEMBL110661 | Spiro[9H-fluorene-9,4'-isothiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010285(2-Chlorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+6nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010284(2,7-DiFluorospiro[9H-fluorene-9,4'-isothiazolidin]...)copy SMILEScopy InChI
Affinity DataIC50: 6.15E+6nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010277(CHEMBL110661 | Spiro[9H-fluorene-9,4'-isothiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+7nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories, Inc.

Curated by ChEMBL
LigandPNGBDBM50010280(2-Fluorospiro[9H-fluorene-9,4'-isothiazolidin]-3'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+7nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7HXMPubMed