Found 59 with Last Name = 'nguyen' and Initial = 'mt' 
Affinity DataIC50: 23nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-dihydroxyphenylalanine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Mus musculus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of human FAAH-mediated hydrolysis of [3H]AEAMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Mus musculus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 377nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 455nMAssay Description:Inhibition of human FAAH-mediated hydrolysis of [3H]AEAMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.94E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.11E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.93E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 5.74E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 6.49E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Competitive inhibition of Bacillus subtilis rhomboid YqgP preincubated for 30 mins followed by FP-Rh addition measured after 1 hr by gel-based ABPP m...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 9.35E+3nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis, Inc.
Curated by ChEMBL
Renovis, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
