Compile Data Set for Download or QSAR
Found 22 with Last Name = 'd''auria' and Initial = 'mv'
TargetPhospholipase A2(Apis mellifera)
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50269843(Bolinaquinone | CHEMBL477692)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50269843(Bolinaquinone | CHEMBL477692)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50269843(Bolinaquinone | CHEMBL477692)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of pig pancreatic group 1 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50269844(CHEMBL517216 | Dysidine)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50577910(CHEMBL4866994)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-LO in A23187/AA-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation measured after 20 mins by RP-HPLC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD15GVPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50577910(CHEMBL4866994)copy SMILES
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of mPGES-1 obtained from IL-beta stimulated human A549 cells microsomes assessed as residual activity by measuring conversion of PGH2 to P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD15GVPubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetPhospholipase A2(Apis mellifera)
Università degli Studi di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28915MQPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"

Curated by ChEMBL
LigandPNGBDBM50347620(RIFAXIMIN | Rifacol | Rifaxidin)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H9XPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"

Curated by ChEMBL
LigandPNGBDBM50448128(CHEMBL3122141)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H9XPubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50434773(CHEMBL2386488)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+4nMAssay Description:Transactivation of FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as beta-galactosidase activity after 18 hrs by luci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59TVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50434774(CHEMBL2386485)copy SMILEScopy InChI
Affinity DataEC50:  2.50E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59TVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50351162(CHEMBL1818098 | CHEMBL1818099)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59TVPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"

Curated by ChEMBL
LigandPNGBDBM50448129(CHEMBL3122144)copy SMILEScopy InChI
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H9XPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50398353(CHEMBL2178596)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RWGPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50398352(CHEMBL2178586)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RWGPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50398351(CHEMBL2178583)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RWGPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£ di Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"

Curated by ChEMBL
LigandPNGBDBM50347620(RIFAXIMIN | Rifacol | Rifaxidin)copy SMILEScopy InChI
Affinity DataEC50:  2.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WP3PubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"

Curated by ChEMBL
LigandPNGBDBM50347619(CHEMBL1649712 | Solomonsterol A)copy SMILEScopy InChI
Affinity DataEC50:  5.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WP3PubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50011369(CHEMBL3260994)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human FXR transfected in human HepG2 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20S3PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Istituto Italiano di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50011369(CHEMBL3260994)copy SMILEScopy InChI
Affinity DataEC50:  200nMAssay Description:Transactivation of human GP-BAR1 transfected in HEK293T cells assessed as induction of intracellular cAMP production after 18 hrs by cAMP responsive ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20S3PubMed