Compile Data Set for Download or QSAR
Found 85 with Last Name = 'burnet' and Initial = 'mw'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-751,75360-1210](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L861Q](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-746,753-1210,P753S](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-746,750-1210,A750P](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [G719C](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [G719S](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 61nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [1-751,75360-1210](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 91nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetIsoform 1 of Misshapen-like kinase 1 (MINK-delta)(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [1-746,753-1210,P753S](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [L861Q](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [1-746,750-1210,A750P](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM241822(US9416123, 3a)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379227(CHEMBL2011293 | US9416123, 7)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379226(CHEMBL2011294 | US9416123, 8)copy SMILEScopy InChI
Affinity DataIC50: 860nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379216(CHEMBL2011296 | US9416123, 10)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379228(CHEMBL2011292 | US9416123, 5)copy SMILEScopy InChI
Affinity DataIC50: 900nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 980nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 990nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379227(CHEMBL2011293 | US9416123, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379224(CHEMBL2011297 | US9416123, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [G719C](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379225(CHEMBL2011295 | US9416123, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379225(CHEMBL2011295 | US9416123, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379223(CHEMBL2011298 | US9416123, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379224(CHEMBL2011297 | US9416123, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379226(CHEMBL2011294 | US9416123, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM241822(US9416123, 3a)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
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