Compile Data Set for Download or QSAR
Found 441 with Last Name = 'krasavin' and Initial = 'my'
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138348(US8877944, 99)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167422(US9073893, 22)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167419(US9073893, 18)copy SMILEScopy InChI
Affinity DataIC50: 23nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167412(US9073893, 5)copy SMILEScopy InChI
Affinity DataIC50: 26nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138348(US8877944, 99)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138344(US8877944, 49)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138344(US8877944, 49)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167427(US9073893, 65)copy SMILEScopy InChI
Affinity DataIC50: 44nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167416(US9073893, 9)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167426(US9073893, 62)copy SMILEScopy InChI
Affinity DataIC50: 70nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138354(US8877944, 105)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138342(US8877944, 47)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138349(US8877944, 103)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138354(US8877944, 105)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138302(US8877944, 4)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167424(US9073893, 31)copy SMILEScopy InChI
Affinity DataIC50: 95nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167413(US9073893, 6)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138325(US8877944, 29)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138325(US8877944, 29)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138327(US8877944, 31)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138327(US8877944, 31)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167414(US9073893, 7)copy SMILEScopy InChI
Affinity DataIC50: 130nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167417(US9073893, 14)copy SMILEScopy InChI
Affinity DataIC50: 130nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167430(US9073893, 63)copy SMILEScopy InChI
Affinity DataIC50: 130nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138301(US8877944, 3)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167411(US9073893, 4)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167428(US9073893, 64)copy SMILES
Affinity DataIC50: 150nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM138298(US8877944, 7)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138346(US8877944, 51)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138300(US8877944, 2)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138324(US8877944, 28)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167425(US9073893, 33)copy SMILEScopy InChI
Affinity DataIC50: 190nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138322(US8877944, 26)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM50110830(CHEMBL3605978)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167410(US9073893, 3)copy SMILEScopy InChI
Affinity DataIC50: 230nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138332(US8877944, 36)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167429(US9073893, 66)copy SMILEScopy InChI
Affinity DataIC50: 230nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167409(US9073893, 2)copy SMILEScopy InChI
Affinity DataIC50: 240nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138333(US8877944, 37)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138334(US8877944, 38)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138326(US8877944, 30)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138331(US8877944, 35)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138323(US8877944, 27)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138335(US8877944, 39)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138298(US8877944, 7)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167423(US9073893, 23)copy SMILEScopy InChI
Affinity DataIC50: 340nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138341(US8877944, 45)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM50110809(CHEMBL3606008 | US11420940, cpd (15))copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138328(US8877944, 32)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138299(US8877944, 1)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
Displayed 1 to 50 (of 441 total ) | Next | Last >>
Jump to: