Compile Data Set for Download or QSAR
Found 602 with Last Name = 'aranibar' and Initial = 'n'
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526620(CHEMBL4460368)copy SMILEScopy InChI
Affinity DataKi:  0.0150nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526622(CHEMBL4442827)copy SMILEScopy InChI
Affinity DataKi:  0.0180nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition of fluorescein labeled probe binding to His-tagged human TYK2 pseudokinase domain (575-869 residues) by Morrison titration based HTRF assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930XJSPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526613(CHEMBL4571920)copy SMILEScopy InChI
Affinity DataKi:  0.0240nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526619(CHEMBL4439957)copy SMILEScopy InChI
Affinity DataKi:  0.0350nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50530394(CHEMBL4561663)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50530394(CHEMBL4561663)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50519523(CHEMBL4440718)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50519523(CHEMBL4440718)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526615(CHEMBL4434711)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526606(CHEMBL4532948 | US11174264, Compound I-3)copy SMILEScopy InChI
Affinity DataKi:  0.0860nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526624(CHEMBL4443010)copy SMILEScopy InChI
Affinity DataKi:  0.0910nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526617(CHEMBL4435047)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526621(CHEMBL4438107)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526603(CHEMBL4293907)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526607(CHEMBL4474801)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526604(CHEMBL4561123)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526610(CHEMBL4453441)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526616(CHEMBL4579439)copy SMILEScopy InChI
Affinity DataKi:  0.220nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526605(CHEMBL4438296)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526612(CHEMBL4543066)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526611(CHEMBL4585272)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526608(CHEMBL4547009)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526623(CHEMBL4466139 | US11174264, Compound I-4)copy SMILEScopy InChI
Affinity DataKi:  0.340nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526618(CHEMBL4437714)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526609(CHEMBL4454109)copy SMILEScopy InChI
Affinity DataKi:  0.480nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526614(CHEMBL4517542)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 domain (575 to 869 residues) (unknown origin) measured after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50530395(CHEMBL4444178)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50530395(CHEMBL4444178)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of TYK2 JH2 (unknown origin) by morrison titration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DMQPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526613(CHEMBL4571920)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526620(CHEMBL4460368)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526606(CHEMBL4532948 | US11174264, Compound I-3)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526619(CHEMBL4439957)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526622(CHEMBL4442827)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526605(CHEMBL4438296)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526617(CHEMBL4435047)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526622(CHEMBL4442827)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/IL2-induced STAT phosphorylation preincubated for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526616(CHEMBL4579439)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526606(CHEMBL4532948 | US11174264, Compound I-3)copy SMILEScopy InChI
Affinity DataKi:  81nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/IL2-induced STAT phosphorylation preincubated for 1 hr followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526612(CHEMBL4543066)copy SMILEScopy InChI
Affinity DataKi:  84nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526619(CHEMBL4439957)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/IL2-induced STAT phosphorylation preincubated for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526620(CHEMBL4460368)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/IL2-induced STAT phosphorylation preincubated for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526610(CHEMBL4453441)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526623(CHEMBL4466139 | US11174264, Compound I-4)copy SMILEScopy InChI
Affinity DataKi:  94nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526603(CHEMBL4293907)copy SMILEScopy InChI
Affinity DataKi:  96nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526604(CHEMBL4561123)copy SMILEScopy InChI
Affinity DataKi:  99nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526615(CHEMBL4434711)copy SMILEScopy InChI
Affinity DataKi:  111nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526608(CHEMBL4547009)copy SMILEScopy InChI
Affinity DataKi:  131nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526609(CHEMBL4454109)copy SMILEScopy InChI
Affinity DataKi:  135nMAssay Description:Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50526613(CHEMBL4571920)copy SMILEScopy InChI
Affinity DataKi:  136nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/IL2-induced STAT phosphorylation preincubated for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FKXPubMed
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