Compile Data Set for Download or QSAR
Found 59 with Last Name = 'deng' and Initial = 'n'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527916(CHEMBL4446962)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264216((2R)-N-(3-{5-chloro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264217((2R)-N-(3-{5-bromo- 2-[(3-methoxy-1- methyl-1H-pyr...)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264214((2R)-N-(3-{2-[(3- Methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527915(CHEMBL4441479)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264204((2R)-N-(3-{5-Fluoro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMedDrugBank
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527911(CHEMBL4544007)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527919(CHEMBL4466590)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527923(CHEMBL4536860)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527909(CHEMBL4452410)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264216((2R)-N-(3-{5-chloro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 60nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527914(CHEMBL4444782)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527919(CHEMBL4466590)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264217((2R)-N-(3-{5-bromo- 2-[(3-methoxy-1- methyl-1H-pyr...)copy SMILES
Affinity DataIC50: 94nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264204((2R)-N-(3-{5-Fluoro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527913(CHEMBL4449567)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264214((2R)-N-(3-{2-[(3- Methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527917(CHEMBL4588587)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527913(CHEMBL4449567)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of JAK1 in human NCI-H1975 cells assessed as decrease in STAT3 phosphorylation measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527923(CHEMBL4536860)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527920(CHEMBL4466247)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527914(CHEMBL4444782)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527912(CHEMBL4553035)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527916(CHEMBL4446962)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527918(CHEMBL4551327)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264217((2R)-N-(3-{5-bromo- 2-[(3-methoxy-1- methyl-1H-pyr...)copy SMILES
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527921(CHEMBL4588128)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264216((2R)-N-(3-{5-chloro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527910(CHEMBL4517840)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527915(CHEMBL4441479)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527911(CHEMBL4544007)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527922(CHEMBL4476801)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527909(CHEMBL4452410)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264214((2R)-N-(3-{2-[(3- Methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264204((2R)-N-(3-{5-Fluoro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527919(CHEMBL4466590)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264217((2R)-N-(3-{5-bromo- 2-[(3-methoxy-1- methyl-1H-pyr...)copy SMILES
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264216((2R)-N-(3-{5-chloro- 2-[(3-methoxy-1- methyl-1H-py...)copy SMILES
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527920(CHEMBL4466247)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527918(CHEMBL4551327)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527919(CHEMBL4466590)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetCytochrome P450 4B1(Homo sapiens)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM264212((2R)-N-(3-{2-[(3- methoxy-1-methyl- 1H-pyrazol-4-y...)copy SMILES
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cytochrome P450More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50527921(CHEMBL4588128)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-labeled GEEPLYWSFPAKKK-NH2 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JDFPubMed
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