Compile Data Set for Download or QSAR
Found 48 with Last Name = 'grazier' and Initial = 'n'
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26359((2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104843(CHEMBL419578 | N-[3-(3-Bromo-4-fluoro-phenyl)-2,2-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104846(CHEMBL113443 | N-[3-(2,5-Dichloro-phenyl)-2,2-dime...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104848(CHEMBL112903 | N-[3-(3-Ethyl-4-fluoro-phenyl)-2,2-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104856(CHEMBL51363 | N-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26357(3-chloroindole compound, 18 | methyl (2Z)-3-[(3-ch...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26360((2Z)-3-[(3-bromo-1H-indol-7-yl)amino]-2-cyano-N,N-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26354(2-{[(3-chloro-1H-indol-7-yl)amino]({[(3S)-2-oxo-1-...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104852(CHEMBL321198 | N-[3-(3-Methoxy-phenyl)-2,2-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104842(CHEMBL297962 | N-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104862(CHEMBL110637 | N-[3-(4-Fluoro-3-isopropyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26351(2-methylbenzofuran compound, 2 | 2-{[(2-methyl-1-b...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104855(CHEMBL109362 | N-[3-(4-Fluoro-3-methyl-phenyl)-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104853(CHEMBL110578 | N-[2-(2,5-Dichloro-phenyl)-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26364((3S)-1-(3-chloro-1H-indol-7-yl)-2-cyano-2-oxo-1-[2...)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104860(CHEMBL113620 | N-(2,2-Dimethyl-3-phenyl-cyclopropa...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104863(CHEMBL112899 | N-[2-(3-Bromo-4-fluoro-phenyl)-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26350((S)-1-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)aze...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26352(2-{[(3-methyl-1H-indol-7-yl)amino]({[(3S)-2-oxo-1-...)copy SMILEScopy InChI
Affinity DataIC50: 114nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26358((2Z)-2-cyano-N,N-dimethyl-3-[(3-methyl-1H-indol-7-...)copy SMILEScopy InChI
Affinity DataIC50: 118nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104854(CHEMBL114393 | N-[2-(2,3-Dihydro-benzofuran-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104861(CHEMBL331141 | N-[2-(3-Chloro-phenyl)-cyclopropane...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26361((2Z)-2-cyano-3-[(3-cyano-1H-indol-7-yl)amino]-N,N-...)copy SMILEScopy InChI
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26363((3S)-2-cyano-1-(3-methyl-1H-indol-7-yl)-2-oxo-1-[2...)copy SMILEScopy InChI
Affinity DataIC50: 336nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26353(2-[(1H-indol-7-ylamino)({[(3S)-2-oxo-1-[2-oxo-2-(p...)copy SMILEScopy InChI
Affinity DataIC50: 430nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104851(CHEMBL114342 | N-[2-(3-Methoxy-phenyl)-cyclopropan...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26355(indole-7-yl compound, 16 | methyl (2Z)-2-cyano-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 650nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104847(CHEMBL112146 | N-[2-(2-Chloro-phenyl)-cyclopropane...)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104845(CHEMBL113369 | N-[2-(4-Fluoro-phenyl)-cyclopropane...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104858(CHEMBL110029 | N-[2-(3-Nitro-phenyl)-cyclopropanec...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104859(CHEMBL113462 | N-[2-(4-Chloro-phenyl)-cyclopropane...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 3.36E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104849(CHEMBL113201 | N-(2-Phenyl-cyclopropanecarbonyl)-g...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26356(indazol-7-yl compound, 17 | methyl (2Z)-2-cyano-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM26362(3-carboxamide indole compound, 23 | 7-{[(1Z)-2-cya...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V12332PubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104857(CHEMBL333603 | N-[2-(4-Nitro-phenyl)-cyclopropanec...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104850(CHEMBL112867 | N-[2-(4-Isopropyl-phenyl)-cycloprop...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed