Compile Data Set for Download or QSAR
Found 355 with Last Name = 'haynes' and Initial = 'n'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100437(US8501732, I-1)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100549(US8501732, I-109)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100550(US8501732, I-110)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100445(US8501732, I-9)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018759(CHEMBL3291350)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018760(CHEMBL3291357)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100609(US8501732, I-169)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018761(CHEMBL3291348)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100551(US8501732, I-111)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100573(US8501732, I-133)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100552(US8501732, I-112)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018793(CHEMBL3291344)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018761(CHEMBL3291348)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100553(US8501732, I-113)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100448(US8501732, I-12)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100574(US8501732, I-134)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100438(US8501732, I-2)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100554(US8501732, I-114)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018759(CHEMBL3291350)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100575(US8501732, I-135)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100556(US8501732, I-116)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100555(US8501732, I-115)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018795(CHEMBL3291339)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100439(US8501732, I-3)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018769(CHEMBL3291346)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018797(CHEMBL3291345)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018760(CHEMBL3291357)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100610(US8501732, I-170)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100557(US8501732, I-117)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018794(CHEMBL3291340)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100502(US8501732, I-62)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100558(US8501732, I-118)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018793(CHEMBL3291344)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM50392983(CHEMBL2152383)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK1 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22808P8PubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100590(US8501732, I-150)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100576(US8501732, I-136)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100577(US8501732, I-137)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM50392984(CHEMBL2152384)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK1 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22808P8PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018769(CHEMBL3291346)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018798(CHEMBL3291342)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018797(CHEMBL3291345)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100469(US8501732, I-29)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100578(US8501732, I-138)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100579(US8501732, I-139)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100559(US8501732, I-119)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018799(CHEMBL3291347)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50018802(CHEMBL3291354)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CPFPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100443(US8501732, I-7)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100440(US8501732, I-4)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM100580(US8501732, I-140)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SP9US Patent
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