Compile Data Set for Download or QSAR
Found 489 with Last Name = 'hossain' and Initial = 'n'
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436912(CHEMBL2401804)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436910(CHEMBL2401853)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436916(CHEMBL2401800)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436906(CHEMBL2401857)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436907(CHEMBL2401856)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436904(CHEMBL2401859)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436905(CHEMBL2401858)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436908(CHEMBL2401855)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436913(CHEMBL2401803)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436903(CHEMBL2401860)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436899(CHEMBL2401864)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436918(CHEMBL2401798)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436902(CHEMBL2401861)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436911(CHEMBL2401805)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436917(CHEMBL2401799)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436914(CHEMBL2401802)copy SMILEScopy InChI
Affinity DataKi:  186nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436900(CHEMBL2401863)copy SMILEScopy InChI
Affinity DataKi:  195nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436915(CHEMBL2401801)copy SMILEScopy InChI
Affinity DataKi:  207nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436901(CHEMBL2401862)copy SMILEScopy InChI
Affinity DataKi:  435nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50436909(CHEMBL2401854)copy SMILEScopy InChI
Affinity DataKi:  4.85E+3nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50PC8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250114(CHEMBL4104286)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250125(CHEMBL4061359)copy SMILEScopy InChI
Affinity DataIC50: 0.0290nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250115(CHEMBL4086388)copy SMILEScopy InChI
Affinity DataIC50: 0.0320nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 0.0370nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMedDrugBank
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)copy SMILEScopy InChI
Affinity DataIC50: 0.0440nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMedDrugBank
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)copy SMILEScopy InChI
Affinity DataIC50: 0.0490nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141371(US8916600, 5 | US9738632, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 0.0510nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141372(US8916600, 6 | US9738632, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 0.0560nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141379(US8916600, 13 | US9738632, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 0.0620nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250126(CHEMBL4094154)copy SMILEScopy InChI
Affinity DataIC50: 0.0660nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250125(CHEMBL4061359)copy SMILEScopy InChI
Affinity DataIC50: 0.0730nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250114(CHEMBL4104286)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(RAT)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141379(US8916600, 13 | US9738632, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250115(CHEMBL4086388)copy SMILEScopy InChI
Affinity DataIC50: 0.101nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250118(CHEMBL4070346)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50203419(CHEMBL3915997)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250126(CHEMBL4094154)copy SMILEScopy InChI
Affinity DataIC50: 0.132nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(RAT)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(RAT)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250119(CHEMBL4098641)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250116(CHEMBL4066614)copy SMILEScopy InChI
Affinity DataIC50: 0.156nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250112(CHEMBL4072756)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141368(US8916600, 2 | US8916600, 3 | US9738632, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141375(US8916600, 9 | US9738632, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250127(CHEMBL4096557)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141367(US8916600, 1 | US8916600, 4 | US9738632, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50250118(CHEMBL4070346)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
TargetGlucocorticoid receptor(RAT)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Transrepression of glucocorticoid receptor in Wistar rat PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9FH8PubMed
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