Compile Data Set for Download or QSAR
Found 402 with Last Name = 'méthot' and Initial = 'n'
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331776((S)-4,4-dichloro-N-((S)-1-cyano-2-phenylethyl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50372597(CHEMBL272424)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29RTPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331767(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-(4-cyano-2-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331769((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50214542((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCathepsin F(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50214542((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302429(2-(9-(2-hydroxy-2-methylpropyl)-6-(isopentyloxy)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331768((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50372597(CHEMBL272424)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29RTPubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331769((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human Cat K expressed in Ramos cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50270592(2-(6-(2-cyclopropylethoxy)-9-(2-hydroxy-2-methylpr...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270029(2-Amino-N-[(S)-3-diazo-1-(4-iodo-benzyl)-2-oxo-pro...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin C after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125TJMPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50270591(2-(6-chloro-9-(3-hydroxy-3-methylbutyl)-1H-phenant...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302428(2-(9-(2-hydroxy-2-methylpropyl)-6-(4,4,4-trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302421(2-(6-(2-cyclopropylethoxy)-9-(2-hydroxy-2-methylpr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19516((2S)-N-[(3S,5E)-6-(benzenesulfonyl)-4-oxo-1-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin S after 10 minsMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331787((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337659(1-(3-((4-chlorophenyl)ethynyl)benzyl)-3-isopropyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50227631(2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337658(1-(3-((4-chlorophenyl)ethynyl)benzyl)-3-isopropyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337654(1-(3-(cyclopropylethynyl)benzyl)-3-isopropyl-1-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302407(2-(6-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50227631(2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302414(2-(6-chloro-9-(3-cyanopropoxy)-1H-phenanthro[9,10-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302415(2-(9-(2-(1H-pyrrol-1-yl)ethoxy)-6-chloro-1H-phenan...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302418(2-(6-chloro-9-(pyridin-3-ylethynyl)-1H-phenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302419(2-(6-chloro-9-(pyridin-4-ylethynyl)-1H-phenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50271108(2-(6-chloro-9-(3-hydroxy-3-methylbut-1-ynyl)-1H-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302420(2-(6-chloro-9-((1-hydroxycyclopentyl)ethynyl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302424(2-(6-ethyl-9-(3-hydroxy-3-methylbut-1-ynyl)-1H-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302425(2-(6-(cyclopropylethynyl)-9-(3-hydroxy-3-methylbut...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19518((2S)-N-(cyanomethyl)-4-methyl-2-{[(1S)-2,2,2-trifl...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331768((S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human Cat K expressed in Ramos cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331778((S)-N-((S)-1-cyano-2-phenylethyl)-3-methyl-2-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337657(3-isopropyl-1-(3-(phenylethynyl)benzyl)-1-((5-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302426(2-(6-chloro-9-(2-hydroxy-2-methylpropyl)-1H-phenan...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302399(6-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302416(2-(6-chloro-9-(4-(methylsulfonyl)phenyl)-1H-phenan...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302417(2-(6-chloro-9-(3-methoxyprop-1-ynyl)-1H-phenanthro...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337661(1-(3-((4-chlorophenyl)ethynyl)benzyl)-3-isopropyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302427(2-(6-(cyclopropylmethoxy)-9-(2-hydroxy-2-methylpro...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302430(2-(9-(2-hydroxy-2-methylpropyl)-6-isobutoxy-1H-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331767(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-(4-cyano-2-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human Cat K expressed in Ramos cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331770(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50302403(6,9-dibromo-2-(2-chloro-6-fluorophenyl)-1H-phenant...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PKKPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337660(3-isopropyl-1-(3-(pyridin-3-ylethynyl)benzyl)-1-(3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337656(1-((5-(cyclopentylethynyl)pyridin-3-yl)methyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337653(1-(biphenyl-3-ylmethyl)-3-isopropyl-1-(3-(phenylet...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5VNPPubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168766(3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q1XPubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331771((S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R8DPubMed
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