Compile Data Set for Download or QSAR
Found 406 with Last Name = 'namdev' and Initial = 'n'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  1.09nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116624(3-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116623(4-Dimethylamino-N-[5-(3-hydroxy-phenyl)-4-methyl-2...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116620(4-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  13.2nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  14.7nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116624(3-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  23.3nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116624(3-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  56.5nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116623(4-Dimethylamino-N-[5-(3-hydroxy-phenyl)-4-methyl-2...)copy SMILEScopy InChI
Affinity DataKi:  57nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  65nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  86nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116620(4-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  87nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  122nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  147nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  207nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  246nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  775nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)copy SMILEScopy InChI
Affinity DataKi:  893nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116623(4-Dimethylamino-N-[5-(3-hydroxy-phenyl)-4-methyl-2...)copy SMILEScopy InChI
Affinity DataKi:  1.46E+3nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116620(4-Guanidino-N-[5-(3-hydroxy-phenyl)-4-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.74E+3nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  2.18E+3nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116622(CHEMBL117457 | N-[5-(3-Hydroxy-phenyl)-4-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi: >3.40E+3nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J8RPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108434(US8609688, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.44nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108434(US8609688, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.44nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108430(US8609688, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108430(US8609688, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108428(US8609688, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.63nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108428(US8609688, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.63nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM130225(US8815854, 14)copy SMILEScopy InChI
Affinity DataIC50: 1.69nMpH: 8.0Assay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67FMRUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108440(US8609688, 18)copy SMILEScopy InChI
Affinity DataIC50: 1.79nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108440(US8609688, 18)copy SMILEScopy InChI
Affinity DataIC50: 1.79nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108436(US8609688, 14)copy SMILEScopy InChI
Affinity DataIC50: 1.84nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108436(US8609688, 14)copy SMILEScopy InChI
Affinity DataIC50: 1.84nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM130222(US8815854, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.99nMpH: 8.0Assay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67FMRUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108435(US8609688, 13)copy SMILEScopy InChI
Affinity DataIC50: 2.15nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108435(US8609688, 13)copy SMILEScopy InChI
Affinity DataIC50: 2.15nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108429(US8609688, 7)copy SMILEScopy InChI
Affinity DataIC50: 2.45nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108429(US8609688, 7)copy SMILEScopy InChI
Affinity DataIC50: 2.45nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536170(CHEMBL4544109)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108431(US8609688, 9)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108431(US8609688, 9)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
Displayed 1 to 50 (of 406 total ) | Next | Last >>
Jump to: