Affinity DataIC50: 1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human MCF7 cells assessed as inhibition of E2-induced response by dual luciferase report...More data for this Ligand-Target Pair
Affinity DataIC50: 613nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Takeda Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.68E+3nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Fluormone ES2 from full length recombinant human untagged ERalpha expressed in Sf insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute of Health Sciences
Curated by ChEMBL
National Institute of Health Sciences
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute of Health Sciences
Curated by ChEMBL
National Institute of Health Sciences
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute of Health Sciences
Curated by ChEMBL
National Institute of Health Sciences
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-fused ERalpha expressed in HEk293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute of Health Sciences
Curated by ChEMBL
National Institute of Health Sciences
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
National Institute of Health Sciences
Curated by ChEMBL
National Institute of Health Sciences
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as induction of transcriptional activity ...More data for this Ligand-Target Pair
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