Compile Data Set for Download or QSAR
Found 191 with Last Name = 'osherov' and Initial = 'n'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50040294(5-[2-(2,5-Dihydroxy-phenyl)-vinyl]-2-hydroxy-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of p56lck autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8DNCPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036687((E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036698((E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5148((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-{3-[(2E)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 340nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036691((E)-3-[3-(Benzothiazol-2-ylsulfanylmethyl)-4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4293((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5164((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxyphenyl)eth-1...)copy SMILEScopy InChI
Affinity DataIC50: 380nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5149((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036688(2-[5-((E)-2-Carbamoyl-2-cyano-vinyl)-2-hydroxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5150((2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50046762(7,8-Dihydroxy-isoquinoline-3-carboxylic acid amide...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2W33
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4284((5,6-Dihydroxyindanylidene)malononitrile | 2-(5,6-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4294((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-fluorophenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5151((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5154((2E)-2-cyano-N-{6-[(2E)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 700nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036679((E)-2-Cyano-3-[4-hydroxy-3-methoxy-5-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5153((2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 700nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4303((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpr...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036688(2-[5-((E)-2-Carbamoyl-2-cyano-vinyl)-2-hydroxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036678(3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5165((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 850nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4305((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4295((2E)-3-(3,4-dihydroxyphenyl)-2-[(4-methylphenyl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4306((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylet...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5166((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 940nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50040296(5-[2-(3,4-Dihydroxy-phenyl)-ethyl]-2-hydroxy-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56lck autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8DNCPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50038203(5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-2-hydroxy-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56lck autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8DNCPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50029199(7,8-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2W33
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50280317(7,8-Dihydroxy-isoquinoline-3-carboxylic acid pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2W33
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036686((E)-3-(3-Benzylsulfanylmethyl-4,5-dihydroxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4308((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbu...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4307((2E)-N-(2-chlorophenyl)-2-cyano-3-(3,4-dihydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4296((2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-eneni...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5155((2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50029199(7,8-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2W33
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM50029221(7,8-Dihydroxy-isoquinoline-3-carboxylic acid phene...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2W33
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036700((E)-3-[3-(Benzooxazol-2-ylsulfanylmethyl)-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4309(Tyrphostin deriv. 58 | ethyl 2-[(2E)-2-cyano-3-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4297((2E)-2-[(2-chlorophenyl)carbonyl]-3-(3,4-dihydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036701(2-Cyano-3-[4-hydroxy-3-(4-hydroxy-phenylsulfanylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4310((2E)-2-cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5156((2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GSZPubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036680((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfan...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
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