TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 78nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 98nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PNP using MSEG as substrate preincubated with inhibitor within 10 to 20 mins measured after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataEC50: 6.5nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Academy of Sciences of the Czech Republic
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
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