Compile Data Set for Download or QSAR
Found 400 with Last Name = 'parr' and Initial = 'n'
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341447(4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(h...)copy SMILEScopy InChI
Affinity DataKi:  0.251nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133948((S)-2-[(3aS,6S,6aR)-4-(6-Hydroxymethyl-benzothiazo...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205359(CHEMBL3917428)copy SMILEScopy InChI
Affinity DataKi:  0.316nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205360(CHEMBL3921827)copy SMILEScopy InChI
Affinity DataKi:  0.398nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17156(3-(4-{[3-(3-methoxy-4-{[(2-methylphenyl)carbamoyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.501nM ΔG°:  -52.5kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QWVPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205353(CHEMBL3947980)copy SMILEScopy InChI
Affinity DataKi:  0.501nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205367(CHEMBL3917794)copy SMILEScopy InChI
Affinity DataKi:  0.501nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205361(CHEMBL3893197)copy SMILEScopy InChI
Affinity DataKi:  0.631nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17196((3R)-3-{4-[2-(3-methoxy-4-{[(2-methylphenyl)carbam...)copy SMILEScopy InChI
Affinity DataKi:  0.790nM ΔG°:  -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QWVPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205358(CHEMBL3898341)copy SMILEScopy InChI
Affinity DataKi:  0.794nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMedDrugBank
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205369(CHEMBL3907368)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205365(CHEMBL3925977)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205355(CHEMBL3952802)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205362(CHEMBL3896541)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205356(CHEMBL3967709)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205364(CHEMBL3935303)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133960((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205357(CHEMBL3925332)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133962((3S,3aR,6aS)-4-({(2S)-1-[(5-Chloro-3-methyl-1-benz...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17165(3-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino}phen...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QWVPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205354(CHEMBL3926412)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205366(CHEMBL3953018)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17191(3-(3-{[3-(4-{[(2-methylphenyl)carbamoyl]amino}phen...)copy SMILEScopy InChI
Affinity DataKi:  3.98nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QWVPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133951(2-{(3S,3aR,6aS)-4-[(S)-1-(4-Isopropyl-phenylcarbam...)copy SMILEScopy InChI
Affinity DataKi:  7.40nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205353(CHEMBL3947980)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133981((2S)-2-{[(3aS,6S,6aR)-4-(Cyclopropylcarbonyl)-6-me...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133989((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341447(4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(h...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetGenome polyprotein(Human rhinovirus B)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133961((S)-2-{(3aS,6S,6aR)-4-[5-(Difluoro-methanesulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133952((S)-2-((3aS,6S,6aR)-4-Benzothiazol-2-yl-6-methyl-5...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205364(CHEMBL3935303)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205358(CHEMBL3898341)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133969((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133957((S)-2-[(3aS,6S,6aR)-6-Methyl-4-((2R,3S)-2-(S)-meth...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205354(CHEMBL3926412)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205361(CHEMBL3893197)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205353(CHEMBL3947980)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Antagonist activity at adrenergic alpha1B receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetGenome polyprotein(Human rhinovirus B)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133973((S)-2-[(3aS,6S,6aR)-4-(6-Fluoro-benzothiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133980((2S)-2-{[(3aS,6S,6aR)-4-(Cyclopropylcarbonyl)-6-me...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133950((S)-2-[(3aS,6S,6aR)-6-Methyl-5-oxo-4-(6-trifluorom...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205353(CHEMBL3947980)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133992((3S,3aR,6aS)-4-[(S)-1-(Biphenyl-4-carbonyl)-pyrrol...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133953((S)-2-((3aS,6S,6aR)-6-Methyl-5-oxo-4-thiazolo[5,4-...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetGenome polyprotein(Human rhinovirus B)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133974((S)-2-[(3aS,6S,6aR)-4-(5-Methoxy-benzothiazol-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50205359(CHEMBL3917428)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133975((S)-2-[(3aS,6S,6aR)-6-Methyl-4-(6-nitro-benzothiaz...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM17188(3-(4-{[3-(3-methoxy-4-{[(2-methylphenyl)carbamoyl]...)copy SMILEScopy InChI
Affinity DataKi:  25.1nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QWVPubMed
TargetGenome polyprotein(Human rhinovirus B)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50133959((S)-2-[(3aS,6S,6aR)-4-(5-Chloro-benzothiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
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