Compile Data Set for Download or QSAR
Found 25 with Last Name = 'seneca' and Initial = 'n'
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]Pentazocine from rat sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methylspiperone from dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]tiotidine from human histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]HEAT from adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetSodium-dependent serotonin transporter(MOUSE)
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM86422(CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...)copy SMILEScopy InChI
Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50477824(CHEMBL252766)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]alpha-methylhistamine from human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)copy SMILEScopy InChI
Affinity DataKi:  9.90nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GFMPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50477826(CHEMBL252765)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50477823(CHEMBL252969)copy SMILEScopy InChI
Affinity DataKi:  205nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50477825(CHEMBL254850)copy SMILEScopy InChI
Affinity DataKi:  377nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)copy SMILEScopy InChI
Affinity DataKi:  7.05E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
TargetSodium-dependent serotonin transporter(MOUSE)
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM84738(CAS_16105-77-4 | Fenfluramine | Fenfluramine (+) |...)copy SMILEScopy InChI
Affinity DataKi:  7.05E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  8.11E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
TargetSodium-dependent dopamine transporter(MOUSE)
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM22167(1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
Target5-hydroxytryptamine receptor 2C(Mus musculus (Mouse))
National Institutes of Health

Curated by PDSP Ki Database
LigandPNGBDBM85098(N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-y...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ28J1PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)copy SMILEScopy InChI
Affinity DataKd:  7.20nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RSQPubMed