Compile Data Set for Download or QSAR
Found 160 with Last Name = 'shibata' and Initial = 'n'
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459869(CHEMBL4227715)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459874(CHEMBL4226259)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PGPH activity of human 26S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550011(CHEMBL4747168)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HPGDSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459873(CHEMBL4225186)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279265(CHEMBL4162041)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459875(CHEMBL4226844)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459868(CHEMBL4225339)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human HPGDS using [14C]-PGH2 as substrate preincubated for 1 min in presence of MgCl2 followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50587271(CHEMBL5075403)copy SMILES
Affinity DataIC50: 140nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50432548(LACTACYSTIN)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50587270(CHEMBL5076100)copy SMILES
Affinity DataIC50: 170nMAssay Description:Inhibition of H-PGDS (unknown origin) using fluorescent probe by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157KTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459866(CHEMBL4226899)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459871(CHEMBL4226314)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1VR7PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458013(CHEMBL4215864)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 211nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V4106TPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550010(CHEMBL4762935)copy SMILES
Affinity DataIC50: 266nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458009(CHEMBL4205518)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550009(CHEMBL4758395)copy SMILES
Affinity DataIC50: 300nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50463722(CHEMBL4238186)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550009(CHEMBL4758395)copy SMILES
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50550010(CHEMBL4762935)copy SMILES
Affinity DataIC50: 320nMAssay Description:Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q13PubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458008(CHEMBL4204198)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Boc-LRR-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TNPPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458009(CHEMBL4205518)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458014(CHEMBL4206039)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458014(CHEMBL4206039)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458007(CHEMBL4209883)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458004(CHEMBL4210397)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6TV7PubMed
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