Found 96 with Last Name = 'sweeney' and Initial = 'n' 
Affinity DataIC50: 2.60nMAssay Description:Agonist activity at human GST-tagged estrogen receptor alpha ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2.80nMAssay Description:Agonist activity at human GST-tagged estrogen receptor beta ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Agonist activity at human GST-tagged estrogen receptor beta ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Concordia University of Wisconsin
Concordia University of Wisconsin
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Concordia University of Wisconsin
Concordia University of Wisconsin
Affinity DataIC50: 2.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Agonist activity at human GST-tagged estrogen receptor alpha ligand binding domain assessed as coactivator peptide PGC1a recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+4nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.65E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7.85E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, assays without and with inhibitors were performed in Greiner 96-well clear bottom plates with a total assay volume of 200 μL. The assay...More data for this Ligand-Target Pair
Affinity DataIC50: 7.88E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 8.66E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+5nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.88E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7.25E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
Affinity DataEC50: 6.29E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Binding affinity to human GST-tagged estrogen receptor beta ligand binding domain after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0220nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based lucif...More data for this Ligand-Target Pair
