Compile Data Set for Download or QSAR
Found 39 with Last Name = 'turner' and Initial = 'n'
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)copy SMILEScopy InChI
Affinity DataKi:  6.80E+3nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85115(Cyclophilin Inhibitor, 3a)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85118(Cyclophilin Inhibitor, 3d)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85119(Cyclophilin Inhibitor, 3e)copy SMILEScopy InChI
Affinity DataKi:  2.07E+5nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to PPIase in vitro assay. The PPIase assay assesses the abil9ity of l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270350(2,5-Anhydro-1-deoxy-1-(3,4-dichlorobenzylamino)-D-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Trypanosoma brucei phosphofructokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270352((2S,3S,4S,5R)-N-cycloheptyl-5-((cycloheptylamino)m...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270447((2S,3S,4S,5R)-N-(3,4-dichlorobenzyl)-5-((cyclohept...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Trypanosoma brucei phosphofructokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270348((2S,3S,4S,5R)-5-((3,4-dichlorobenzylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Trypanosoma brucei phosphofructokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270448((2S,3S,4S,5R)-5-((cycloheptylamino)methyl)-3,4-dih...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270344(2,5-Anhydro-1-deoxy-1-(cycloheptylamino)-D-mannito...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270351((2S,3S,4S,5R)-5-((3,4-dichlorobenzylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of Trypanosoma brucei phosphofructokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50454541(CHEMBL4210493)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of recombinant human GABA A alpha2beta2gamma2 receptor expressed in CHO-K1 cells incubated at room temperature for 15 mins before the GABA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32ZB2PubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270460(2,5-Anhydro-1-deoxy-1-(3,4-dichlorobenzylamino)-D-...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of Trypanosoma brucei phosphofructokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50454543(CHEMBL4217850)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+5nMAssay Description:Inhibition of recombinant human GABA A alpha2beta2gamma2 receptor expressed in CHO-K1 cells incubated at room temperature for 15 mins before the GABA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32ZB2PubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270341((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270338((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50454540(CHEMBL4213450)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+6nMAssay Description:Inhibition of recombinant human GABA A alpha2beta2gamma2 receptor expressed in CHO-K1 cells incubated at room temperature for 15 mins before the GABA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32ZB2PubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270347((2R,3S,4S,5R)-2-(((1R,2S,4R)-bicyclo[2.2.1]heptan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270349((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(naphtha...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270343((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(naphtha...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270345((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-3-methylbu...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50454542(CHEMBL4206129)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+6nMAssay Description:Inhibition of recombinant human GABA A alpha2beta2gamma2 receptor expressed in CHO-K1 cells incubated at room temperature for 15 mins before the GABA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32ZB2PubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270474((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((pentan-2-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270340((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270449((2R,3S,4S,5R)-2-((cyclopentylamino)methyl)-5-(hydr...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPyruvate kinase(Leishmania mexicana)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50270339((2R,3S,4S,5R)-2-((cyclobutylamino)methyl)-5-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+6nMAssay Description:Inhibition of Leishmania mexicana pyruvate kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99JRPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85120(Cyclophilin Inhibitor, 3f)copy SMILEScopy InChI
Affinity DataKd:  1.33E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85119(Cyclophilin Inhibitor, 3e)copy SMILEScopy InChI
Affinity DataKd:  1.13E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85118(Cyclophilin Inhibitor, 3d)copy SMILEScopy InChI
Affinity DataKd:  8.51E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)copy SMILEScopy InChI
Affinity DataKd:  3.19E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)copy SMILEScopy InChI
Affinity DataKd:  7.26E+4nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85115(Cyclophilin Inhibitor, 3a)copy SMILEScopy InChI
Affinity DataKd:  1.28E+5nMAssay Description:Electrospray mass spectrometry assay is a immunophilin-ligand binding assay which allows us to rapidly probe the affinity of potential inhibitors for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85115(Cyclophilin Inhibitor, 3a)copy SMILEScopy InChI
Affinity DataKd:  2.28E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)copy SMILEScopy InChI
Affinity DataKd:  1.59E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85117(Cyclophilin Inhibitor, 3c)copy SMILEScopy InChI
Affinity DataKd:  2.96E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85116(Cyclophilin Inhibitor, 15 | Cyclophilin Inhibitor,...)copy SMILEScopy InChI
Affinity DataKd: >5.00E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
The University of Edinburgh

LigandPNGBDBM85119(Cyclophilin Inhibitor, 3e)copy SMILEScopy InChI
Affinity DataKd:  2.19E+4nMAssay Description:The promising ligand from the results obtained from ESI-MS assay are subjected to fluorescence in vitro assay. The fluorescence assay takes advantag...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K77MKPubMed