Compile Data Set for Download or QSAR
Found 586 with Last Name = 'westlund' and Initial = 'n'
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574409(CHEMBL4873534)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574409(CHEMBL4873534)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536170(CHEMBL4544109)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574409(CHEMBL4873534)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536172(CHEMBL4513257)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574409(CHEMBL4873534)copy SMILES
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397783(CHEMBL2177833)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574413(CHEMBL4873959)copy SMILES
Affinity DataIC50: 5.30nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536178(CHEMBL4528363)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536170(CHEMBL4544109)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574412(CHEMBL4856006)copy SMILES
Affinity DataIC50: 6nMAssay Description:Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536169(CHEMBL4519558)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574401(CHEMBL4855559)copy SMILES
Affinity DataIC50: 7.20nMAssay Description:Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574414(CHEMBL4850845)copy SMILES
Affinity DataIC50: 7.30nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397780(CHEMBL2177831)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574406(CHEMBL4851230)copy SMILES
Affinity DataIC50: 8nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574410(CHEMBL4851860)copy SMILES
Affinity DataIC50: 8.10nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574401(CHEMBL4855559)copy SMILES
Affinity DataIC50: 8.10nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536168(CHEMBL4574111)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full length active AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574412(CHEMBL4856006)copy SMILES
Affinity DataIC50: 9.30nMAssay Description:Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574410(CHEMBL4851860)copy SMILES
Affinity DataIC50: 11nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536173(CHEMBL4546484)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574413(CHEMBL4873959)copy SMILES
Affinity DataIC50: 14nMAssay Description:Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397800(CHEMBL2177817)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536181(CHEMBL4576518)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397796(CHEMBL2177828)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574412(CHEMBL4856006)copy SMILES
Affinity DataIC50: 15nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574401(CHEMBL4855559)copy SMILES
Affinity DataIC50: 15nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574402(CHEMBL4878045)copy SMILES
Affinity DataIC50: 15nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50536167(CHEMBL4523032)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of full length active AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3CCMPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397796(CHEMBL2177828)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetEstrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50574416(CHEMBL4877124)copy SMILES
Affinity DataIC50: 17nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RG4PubMed
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