Compile Data Set for Download or QSAR
Found 77 with Last Name = 'sachs' and Initial = 'na'
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167083(CHEMBL3800482)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167086(CHEMBL3798212)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167074(CHEMBL3799913)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086213(CHEMBL3425734)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086214(CHEMBL3425744)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086210(CHEMBL3425739)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167084(CHEMBL3798524)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167074(CHEMBL3799913)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086213(CHEMBL3425734)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086220(CHEMBL3425735)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167078(CHEMBL3800198)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086218(CHEMBL3425740)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086211(CHEMBL3425738)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086211(CHEMBL3425738)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086211(CHEMBL3425738)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086211(CHEMBL3425738)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086212(CHEMBL3425737)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167083(CHEMBL3800482)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086219(CHEMBL3425736)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086210(CHEMBL3425739)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086218(CHEMBL3425740)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167086(CHEMBL3798212)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167079(CHEMBL3797723)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086222(CHEMBL3425732)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086221(CHEMBL3425733)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086223(CHEMBL3425731)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086215(CHEMBL3425743 | US9260413, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086217(CHEMBL3425741)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086214(CHEMBL3425744)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086217(CHEMBL3425741)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086234(CHEMBL3425721)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086212(CHEMBL3425737)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167080(CHEMBL3798286)copy SMILEScopy InChI
Affinity DataIC50: 456nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167087(CHEMBL3798113)copy SMILEScopy InChI
Affinity DataIC50: 574nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167092(CHEMBL3797584)copy SMILEScopy InChI
Affinity DataIC50: 672nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086225(CHEMBL3425729)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167082(CHEMBL3797901)copy SMILEScopy InChI
Affinity DataIC50: 706nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167256(CHEMBL3798854)copy SMILEScopy InChI
Affinity DataIC50: 826nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086209(CHEMBL3425722)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167078(CHEMBL3800198)copy SMILEScopy InChI
Affinity DataIC50: 946nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167076(CHEMBL3797305)copy SMILEScopy InChI
Affinity DataIC50: 962nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086218(CHEMBL3425740)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50086215(CHEMBL3425743 | US9260413, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086213(CHEMBL3425734)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after ...More data for this Ligand-Target Pair
TargetLanosterol synthase(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50167076(CHEMBL3797305)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D1BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086210(CHEMBL3425739)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086211(CHEMBL3425738)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35WDZPubMed
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