Compile Data Set for Download or QSAR
Found 41 with Last Name = 'hales' and Initial = 'nj'
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50292299((5S)-3-(3-fluoro-4-(3-methylisoxazol-5-yl)phenyl)-...)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:Inhibition human liver MAOA activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JQRPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159379((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibitory activity against prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50292302(CHEMBL390465 | N-(((S)-3-(3-fluoro-4-(3-methylisox...)copy SMILEScopy InChI
Affinity DataKi:  950nMAssay Description:Inhibition human liver MAOA activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JQRPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159388((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50292301((5R)-5-((1H-1,2,3-triazol-1-yl)methyl)-3-(3-fluoro...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition human liver MAOA activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JQRPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159382((R)-5-(4-Chloro-[1,2,3]triazol-1-ylmethyl)-3-[4-(1...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159372(1-{(R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159385((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159370(1-{(R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159380((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159375(CHEMBL179191 | N-{(S)-3-[4-(1,1-Dioxo-1,2,3,6-tetr...)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159378((R)-5-(4-Bromo-[1,2,3]triazol-1-ylmethyl)-3-[4-(1,...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition human liver MAOA activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JQRPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50292300((5R)-3-(3-fluoro-4-(3-methylisoxazol-5-yl)phenyl)-...)copy SMILEScopy InChI
Affinity DataKi:  2.26E+4nMAssay Description:Inhibition human liver MAOA activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JQRPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159386((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159374((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  4.70E+4nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159371(CHEMBL360090 | Phosphoric acid 1-{(R)-3-[4-(1,1-di...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159373((R)-5-[4-(2,2-Dibromo-vinyl)-[1,2,3]triazol-1-ylme...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159377((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi:  1.02E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159376((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159387((1-{(R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159384((R)-5-[4-((E)-2-Bromo-vinyl)-[1,2,3]triazol-1-ylme...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159383((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
AstraZeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50159381((R)-3-[4-(1,1-Dioxo-1,2,3,6-tetrahydro-1lambda*6*-...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for human liver monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NBSPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042873(5'-(4-Ethoxy-phenylcarbamoyl)-[2,2']bipyridinyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042872(3-phenylsulfonamidocarbonyl-6-(5-phenylsulfonamido...)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042875(CHEMBL125345 | Potassium; [2,2']bipyridinyl-5-carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042877(CHEMBL420149 | N-([2,2']Bipyridinyl-5-carbonyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042874(2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...)copy SMILEScopy InChI
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000866(2-(Oxalyl-amino)-propionic acid (0.25H2O) | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 3.82E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000865(2-(Oxalyl-amino)-propionic acid | CHEMBL314979)copy SMILEScopy InChI
Affinity DataIC50: 9.07E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000407(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000864(CHEMBL314175 | N-(2-Methanesulfonylamino-2-oxo-eth...)copy SMILEScopy InChI
Affinity DataIC50: 4.14E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000863(2-(Oxalyl-amino)-propionic acid | CHEMBL88472)copy SMILEScopy InChI
Affinity DataIC50: 6.21E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylase at 50 ug/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5ZF9PubMed