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Found 662 with Last Name = 'davies' and Initial = 'nl'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508937(CHEMBL4448046)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508939(CHEMBL4443085)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508950(CHEMBL4472439)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508947(CHEMBL4460550)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508938(CHEMBL1984039)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508940(CHEMBL4582512)copy SMILEScopy InChI
Affinity DataKi:  739nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508942(CHEMBL4449849)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508941(CHEMBL4442625)copy SMILEScopy InChI
Affinity DataKi:  4.96E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508941(CHEMBL4442625)copy SMILEScopy InChI
Affinity DataKi:  4.96E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50508936(CHEMBL4590345)copy SMILEScopy InChI
Affinity DataKi:  5.21E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PNHPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of ATM (unknown origin) using p53 as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs by HTRF as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
LigandPNGBDBM50548115(CHEMBL4778773)copy SMILES
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245500(US9428503, 28)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245505(US9428503, 33)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245478(US9428503, 5)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245475(US9428503, 2)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245514(US9428503, 42)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245510(US9428503, 38)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
LigandPNGBDBM50548110(CHEMBL4747532)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245490(US9428503, 17)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
LigandPNGBDBM50162075(CHEMBL3794167)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
LigandPNGBDBM50162074(CHEMBL3792684)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
LigandPNGBDBM50548117(CHEMBL4776026)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245491(US9428503, 18)copy SMILEScopy InChI
Affinity DataIC50: 0.760nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245481(US9428503, 8)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
LigandPNGBDBM50548124(CHEMBL4784602)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
LigandPNGBDBM50548109(CHEMBL4783492)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245489(US9428503, 16)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245519(US9428503, 47)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245479(US9428503, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245525(US9428503, 53)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
LigandPNGBDBM50548121(CHEMBL4754128)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM245477(US9428503, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573136(CHEMBL4875486)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine-protein kinase ATM(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50378199(CHEMBL4163629)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB775PPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50246761(CHEMBL4102501)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
LigandPNGBDBM50548119(CHEMBL4749068)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BHRPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573135(CHEMBL4873217)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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