Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.00145nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0427nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0525nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0741nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.102nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.107nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.195nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.759nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 0.813nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Norwegian Medical Cyclotron Centre, PO Box 4950, Nydalen, N-0424 Oslo, Norway.
Curated by ChEMBL
Norwegian Medical Cyclotron Centre, PO Box 4950, Nydalen, N-0424 Oslo, Norway.
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]Triptorelin from rat full-length gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 2nM ΔG°: -50.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory AS
Curated by ChEMBL
Drug Discovery Laboratory AS
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Mus musculus)
Norwegian Medical Cyclotron Centre, PO Box 4950, Nydalen, N-0424 Oslo, Norway.
Curated by ChEMBL
Norwegian Medical Cyclotron Centre, PO Box 4950, Nydalen, N-0424 Oslo, Norway.
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to mouse gonadotropin-releasing hormone receptor by radioligand displacement assayMore data for this Ligand-Target Pair
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