Compile Data Set for Download or QSAR
Found 86 with Last Name = 'polesskaya' and Initial = 'o'
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of MLK2 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM356235(BDBM50441572 | US10485800, Example 1 | US9814704, ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type human FLT3 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441571(CHEMBL2436982 | US10485800, Example 18 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of wild type human ABL1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441571(CHEMBL2436982 | US10485800, Example 18 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441570(CHEMBL2436976 | US10485800, Example 17 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of wild type human FLT3 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441569(CHEMBL2436981 | US10485800, Example 4 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM356235(BDBM50441572 | US10485800, Example 1 | US9814704, ...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441573(CHEMBL2436979 | US10485800, Example 40 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of MLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441569(CHEMBL2436981 | US10485800, Example 4 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441568(CHEMBL2436983 | US10485800, Example 9 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of wild type human TRKA by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetAurora kinase A(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of wild type human Aurora kinase A by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of wild type human ROCK2 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441571(CHEMBL2436982 | US10485800, Example 18 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetAurora kinase B(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of wild type human Aurora kinase B by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human wild type DLK by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of wild type human c-MET by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInsulin receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type human IR by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of wild type human SGK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 217nMAssay Description:Inhibition of wild type human TRKB by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 257nMAssay Description:Inhibition of wild type human IKKb by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 288nMAssay Description:Inhibition of wild type human IKKb by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetAurora kinase C(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of wild type human Aurora kinase C kinase by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Inhibition of wild type human IGF1R by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of wild type human IKKa by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441569(CHEMBL2436981 | US10485800, Example 4 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441568(CHEMBL2436983 | US10485800, Example 9 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of FLT3-L-stimulated wild type full length human FLT3 autophosphorylation expressed in MEF preincubated for 90 mins followed by FLT3-L sti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 591nMAssay Description:Inhibition of wild type human IKKa by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 661nMAssay Description:Inhibition of wild type human MEKK2 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of FLT3-L-stimulated wild type full length human FLT3 autophosphorylation expressed in MEF preincubated for 90 mins followed by FLT3-L sti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 731nMAssay Description:Inhibition of wild type human SYK by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441570(CHEMBL2436976 | US10485800, Example 17 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of wild type human ROCK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of wild type human CDK1 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetInsulin receptor(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of wild type human IR by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Mus musculus)
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM356235(BDBM50441572 | US10485800, Example 1 | US9814704, ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441573(CHEMBL2436979 | US10485800, Example 40 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human wild type LRRK2 by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441569(CHEMBL2436981 | US10485800, Example 4 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as inhibition of diclofenac metabolism by HPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of wild type human ZAP70 by high throughput ATP-[33P] radiolabeled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
Displayed 1 to 50 (of 86 total ) | Next | Last >>
Jump to: