Compile Data Set for Download or QSAR
Found 373 with Last Name = 'silakari' and Initial = 'o'
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50394355(CHEMBL2159766)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of CCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DWWPubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50394356(CHEMBL2159765)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of CCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DWWPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataKi:  520nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KMNPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50050769(CHEMBL3318019)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KMNPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KMNPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50016784(ALLOPURINOL | BW-56-158 | BW-56158 | CHEBI:40279 |...)copy SMILEScopy InChI
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KMNPubMedDrugBank
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataKi:  8.10E+4nMAssay Description:Inhibition of forskolin-stimulated CFTR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KMNPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM10512(CHEMBL194823 | N-{3-[(6-chloro-1,2,3,4-tetrahydroa...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63V1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50613673(CHEMBL1964259)copy SMILES
Affinity DataIC50: 0.540nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094551(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...)copy SMILEScopy InChI
Affinity DataIC50: 0.601nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094542(1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 0.701nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094539(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462398(CHEMBL4249848)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine iodide as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63V1PubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462402(CHEMBL4249379)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine iodide as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63V1PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126727((S)-4-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-(N-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094540(1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Reversible inhibition of NH2-terminal 6His-tagged FAK catalytic domain (410 to 689 residues) (unknown origin) expressed in Sf9 insect cells using p(G...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094546(3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094532(1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10112((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)copy SMILEScopy InChI
In DepthDetails
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094558(3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094548(1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10109((3Z)-4-[(3R,4S,5R)-4-amino-3,5-dihydroxyhex-1-yn-1...)copy SMILEScopy InChI
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094528(5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094535(1,3-diphenyl-4,7-dihydro-2H-isoindole | CHEMBL1408...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094561(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)copy SMILEScopy InChI
Affinity DataIC50: 4.51nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr HS Gour University

Curated by ChEMBL
LigandPNGBDBM50094541(1,3-Bis-(4-chloro-phenyl)-4,5,6,7-tetrahydro-2H-is...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909WPPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)copy SMILEScopy InChI
In DepthDetails
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039JBPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207475(1-(4-(3-amino-7-fluoro-1H-indazol-4-yl)phenyl)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9C6DPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50404086(CHEMBL341226)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126702(CHEMBL282807 | Isoquinoline-5-sulfonic acid 4-{(S)...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126713(CHEMBL282173 | Isoquinoline-5-sulfonic acid 4-{(S)...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451951(CHEMBL4217941)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9C6DPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451934(CHEMBL4207594)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451935(CHEMBL4208825)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451931(CHEMBL4213552)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50258204(2-(4-tert-butylphenyl)-4-(4-((5-ethyl-1-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DWWPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50366929(CHEMBL1794057)copy SMILEScopy InChI
In DepthDetails
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451962(CHEMBL4214058)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50404085(CHEMBL336619)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613675(CHEMBL5275659)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50126413(CHEMBL287478 | N*1*-[7-(4-Morpholin-4-yl-phenyl)-[...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039JBPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50451932(CHEMBL4204793)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JP6PubMed
LigandPNGBDBM50085415(3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...)copy SMILEScopy InChI
In DepthDetails
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM8813(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9C6DPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50324735((5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant GST-tagged PI3Kgamma incubated for 180 mins using [33P]gamma-ATP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50411888(CHEMBL270421)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BX7PubMed
Displayed 1 to 50 (of 373 total ) | Next | Last >>
Jump to: