Compile Data Set for Download or QSAR
Found 303 with Last Name = 'botrugno' and Initial = 'oa'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TQMPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236453(CHEMBL4068323)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Inhibitory activity against beta-glucosidase of sweet almondMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236360(CHEMBL4066708)copy SMILEScopy InChI
Affinity DataKi:  4.30E+4nMAssay Description:Non-competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated fo...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236359(CHEMBL4086085)copy SMILEScopy InChI
Affinity DataKi:  4.84E+4nMAssay Description:Competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112KNPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM254603(US10214477, Example 5 | US9469597, 4 | US9670136, ...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112KNPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236447(CHEMBL4069817)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50023732(CHEMBL3330339)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TT3PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236444(CHEMBL4090812)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236441(CHEMBL4072541)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50023746(CHEMBL3330328)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TT3PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50078895(CHEMBL3416426)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236456(CHEMBL4081995)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50023741(CHEMBL3330334)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 20 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TT3PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50078896(CHEMBL3416427)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50078893(CHEMBL3416432)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236457(CHEMBL4074211)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155763(CHEMBL3780391)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50078896(CHEMBL3416427)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50078893(CHEMBL3416432)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50078894(CHEMBL3416431)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155766(CHEMBL3780374)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236451(CHEMBL4080514)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50080870(CHEMBL3421673)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TQMPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155767(CHEMBL3780524)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50346863(CHEMBL1797640 | US8765820, 5b)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155767(CHEMBL3780524)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50078894(CHEMBL3416431)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50078895(CHEMBL3416426)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155763(CHEMBL3780391)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University of Roma

Curated by ChEMBL
LigandPNGBDBM50080872(CHEMBL3421675)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833TQMPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155768(CHEMBL3781494)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155765(CHEMBL3781329)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236468(CHEMBL4061143)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155769(CHEMBL3780542)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155765(CHEMBL3781329)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236459(CHEMBL4100964)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236469(CHEMBL4083022)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236470(CHEMBL4099458)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50078892(CHEMBL3416434)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12QFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50023732(CHEMBL3330339)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 20 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TT3PubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236467(CHEMBL4073106)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22809VXPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155770(CHEMBL3781885)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086767PubMed
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