Compile Data Set for Download or QSAR
Found 229 with Last Name = 'levy' and Initial = 'oe'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9690(SCH446211 (SCH6) Analog 23 | tert-butyl N-[(2S)-1-...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -50.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9691(SCH446211 (SCH6) | TERT-BUTYL [(1S)-1-({(1R,2S,5S)...)copy SMILEScopy InChI
Affinity DataKi:  3.80nM ΔG°:  -48.9kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9684(2-methylpropyl N-[(2S)-1-[(3aR,4S,6aR)-4-({1-[({[(...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -46.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9689(SCH446211 (SCH6) Analog 22 | tert-butyl N-[(2S)-1-...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -46.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9686(2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(1R,2S,5S)-...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -46.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9688(SCH446211 (SCH6) Analog 21 | tert-butyl N-[(2S)-1-...)copy SMILEScopy InChI
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9685(2-methylpropyl N-[(2S)-1-[(1S,3aR,6aS)-1-({1-[({[(...)copy SMILEScopy InChI
Affinity DataKi:  15nM ΔG°:  -45.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087641(3-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087645(4-{2-[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piper...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9687(2-methylpropyl N-[(2S)-1-[(1R,2S,5S)-2-({1-[({[(S)...)copy SMILEScopy InChI
Affinity DataKi:  16nM ΔG°:  -45.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9683(2-methylpropyl N-[(2S)-1-[(2S,4R)-4-(tert-butoxy)-...)copy SMILEScopy InChI
Affinity DataKi:  19nM ΔG°:  -44.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087647(CHEMBL162277 | [(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087639((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Concentration of the compound required for classical fast inhibition of cleavage of the chromogenic substrate by human enzyme Coagulation factor X in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9680(2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(8S)-8-({1-...)copy SMILEScopy InChI
Affinity DataKi:  26nM ΔG°:  -44.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9679(2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-...)copy SMILEScopy InChI
Affinity DataKi:  26nM ΔG°:  -44.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9681(2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-...)copy SMILEScopy InChI
Affinity DataKi:  28nM ΔG°:  -43.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9678(2-methylpropyl N-[(2S)-1-[(2S)-2-{[(2S)-1-[({[(S)-...)copy SMILEScopy InChI
Affinity DataKi:  36nM ΔG°:  -43.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9682(2-methylpropyl N-[(1S)-2-[(2S,4R)-4-(tert-butylsul...)copy SMILEScopy InChI
Affinity DataKi:  120nM ΔG°:  -40.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9677(2-methylpropyl N-[(2S)-1-[(2S,4R)-2-({1-[({[(S)-(d...)copy SMILEScopy InChI
Affinity DataKi:  140nM ΔG°:  -39.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9676(2-methylpropyl N-[(1S)-1-cyclohexyl-2-[(2S)-2-({1-...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nM ΔG°:  -29.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98691PubMed
TargetNeprilysin(Homo sapiens (Human))
Salk Biotechnology/Industrial Associates

Curated by ChEMBL
LigandPNGBDBM50044862(2-(2-Benzyl-5-cyano-4-oxo-pentanoylamino)-3-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition constant determined for neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S2XPubMed
TargetNeprilysin(Homo sapiens (Human))
Salk Biotechnology/Industrial Associates

Curated by ChEMBL
LigandPNGBDBM50044861(2-[2-(2-Cyano-acetylamino)-3-phenyl-propionylamino...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition constant determined for Neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S2XPubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Salk Biotechnology/Industrial Associates

Curated by ChEMBL
LigandPNGBDBM50044861(2-[2-(2-Cyano-acetylamino)-3-phenyl-propionylamino...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+4nMAssay Description:Inhibition constant determined for Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S2XPubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Salk Biotechnology/Industrial Associates

Curated by ChEMBL
LigandPNGBDBM50044862(2-(2-Benzyl-5-cyano-4-oxo-pentanoylamino)-3-phenyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition constant determined for angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5S2XPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50083743(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4W1FPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50093056((S)-N-Benzo[1,3]dioxol-5-ylmethyl-4-cyclohexyl-3-{...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VBRPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087644((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50093057((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VBRPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087635(((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087635(((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087635(((R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087638((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087636((R)-N-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087643(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087642(CHEMBL163251 | N-[((S)-1-Carbamimidoyl-2-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetAnionic trypsin(Bos taurus)
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1.37nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International Inc.

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SFVPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50093062((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VBRPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50093066(((S)-4-Cyclohexyl-3-{2-[((R)-5-guanidino-2-phenylm...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VBRPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087637(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50087637(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M5RPubMed
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