TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 83nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 213nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 252nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 255nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 368nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 559nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 567nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataKi: 2.84E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 141nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataIC50: 161nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair
TargetPhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform(Oryctolagus cuniculus (rabbit))
Laboratoires Glaxo
Laboratoires Glaxo
Affinity DataIC50: 180nMAssay Description:The activity of PK is measured by its ability to transfer from [gamma-32P]ATP to phosphorylase b.More data for this Ligand-Target Pair