Compile Data Set for Download or QSAR
Found 96 with Last Name = 'brandt' and Initial = 'p'
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50142916((1S,4R,6S,14S,18R)-14-Cyclopentyloxycarbonylamino-...)copy SMILEScopy InChI
Affinity DataKi:  0.0890nMAssay Description:Inhibition of HCV genotype-1a NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458174(CHEMBL4212267)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease R155K mutant preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458174(CHEMBL4212267)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50366760(CHEMBL2369589)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50142916((1S,4R,6S,14S,18R)-14-Cyclopentyloxycarbonylamino-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease R155K mutant preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458174(CHEMBL4212267)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458171(CHEMBL4208860)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease R155K mutant preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458175(CHEMBL3797556)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458177(CHEMBL3797877)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458179(CHEMBL3798865)copy SMILEScopy InChI
Affinity DataKi:  87nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)copy SMILEScopy InChI
Affinity DataKi:  135nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458173(CHEMBL4217239)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458176(CHEMBL3798789)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458171(CHEMBL4208860)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458172(CHEMBL4213784)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetGenome polyprotein(Hepatitis C virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50458178(CHEMBL4204522)copy SMILEScopy InChI
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of HCV genotype-1a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2RMGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beactica AB

Curated by ChEMBL
LigandPNGBDBM50478032(CHEMBL275658 | GW4511 | GW564511 | GW69564)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B91T8PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beactica AB

Curated by ChEMBL
LigandPNGBDBM50476133(CHEMBL373571 | VRX-480773)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B91T8PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469157(CHEMBL4284736)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501358(CHEMBL3947604)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P1321PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501352(CHEMBL3922978)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P1321PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Beactica AB

Curated by ChEMBL
LigandPNGBDBM1885(3-(5-bromopyridin-2-yl)-1-(2-phenylethyl)thiourea ...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B91T8PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469159(CHEMBL4283840)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501354(CHEMBL3934222)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P1321PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 22nM EC50:  32nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18896(3-(3,5-dibromo-4-{[3-(ethylamino)phenyl]methoxy}ph...)copy SMILEScopy InChI
Affinity DataIC50: 23nM EC50:  49nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469154(CHEMBL4283678)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 36nM EC50:  32nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469165(CHEMBL4291540)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469162(CHEMBL4282733)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469170(CHEMBL4291025)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50501357(CHEMBL3957297)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of full length Escherichia coli His6-tagged LepB expressed in Escherichia coli C43(DE3) using dabcyl-VEVGGTATAGAFSRPGLE-(EDANS) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P1321PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469166(CHEMBL4294422)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18894(3-{3,5-dibromo-4-[(3-bromophenyl)methoxy]phenyl}pr...)copy SMILEScopy InChI
Affinity DataIC50: 60nM EC50:  230nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469169(CHEMBL4292925)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18896(3-(3,5-dibromo-4-{[3-(ethylamino)phenyl]methoxy}ph...)copy SMILEScopy InChI
Affinity DataIC50: 78nM EC50:  23nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18897(3-(3,5-dibromo-4-{[3-(diethylamino)phenyl]methoxy}...)copy SMILEScopy InChI
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 93nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 93nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469164(CHEMBL4287199)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18894(3-{3,5-dibromo-4-[(3-bromophenyl)methoxy]phenyl}pr...)copy SMILEScopy InChI
Affinity DataIC50: 99nM EC50:  380nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R20ZMSPubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469160(CHEMBL4280386)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
TargetSignal peptidase I(Escherichia coli (strain K12))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50469167(CHEMBL4279276)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of Escherichia coli type 1 signal peptidase lepB preincubated for 10 mins followed by Dabcyl-VGGTATAYGAFSRPGLE-(EDANS)-OH substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70JH1PubMed
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