Compile Data Set for Download or QSAR
Found 919 with Last Name = 'di giorgio' and Initial = 'p'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Angelini Pharma S.p.A.

Curated by ChEMBL
LigandPNGBDBM50267626(AZ-11548415 | AZD-1080)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant full length human GSK3beta expressed in Sf21 insect cells using biotinylated-AAEELDSRAGS(PO3H2)PQL peptide as substrate pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930XQ1PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511554(US11059794, Example 6.14 | tert-butyl 4-(2-fluoro-...)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442707(US10647719, Example 1.18 | [6-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 1nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511558(US11059794, Example 6.18 | tert-butyl 4-[2-(2-fluo...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442729(3-fluoro-4-[2-[3-[2-[(4-methyltriazol- | US1064771...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442699(3-fluoro-4-(5-(2-((5-methyl-2H- | BDBM442731 | US1...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442712(US10647719, Example 1.23 | [6-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 1nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511551(US11059794, Example 6.13 | tert-butyl 4-(2-fluoro-...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511579(US11059794, Example 6.39 | tert-butyl 4-(3-fluoro-...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511578(US11059794, Example 6.38 | tert-butyl 4-[2-(5- sul...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511567(US11059794, Example 6.27 | tert-butyl 4-(2,3-diflu...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477064(US10882857, Example 4.02 | US11673888, Example 4.0...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM467326(US10800786, Example 2.01)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3BZTUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM467343(US10800786, Example 2.15)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3BZTUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM467346(US10800786, Example 5.00)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3BZTUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442717(BDBM442732 | US10647719, Example 1.28 | [3-(2,2-di...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442719(US10647719, Example 2.01 | [4-(trifluoromethoxy)ph...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442736(4-[5-[2-cyclopropyl-6-(oxan-4- | US10647719, Examp...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442737(4-[5-[2-cyclopyropyl-6-[(1- | US10647719, Example ...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM477058(US10882857, Example 2.06 | US11673888, Example 2.0...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93GXUS Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM477062(US10882857, Example 4 | US11673888, Example 4 | [3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93GXUS Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM477064(US10882857, Example 4.02 | US11673888, Example 4.0...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ93GXUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511581(US11059794, Example 6.41 | tert-butyl 4-(2-fluoro-...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511585(US11059794, Example 6.45 | tert-butyl 4-[2-[(5-sul...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511524(US11059794, Example 4.00)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511530(4-(piperidin-4- ylmethyl)benzenesulfonamide hydroc...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511538(US11059794, Example 6.00)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511541(US11059794, Example 6.03 | tert-butyl 4-[2-(2,3-di...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM475790(US10849881, Example 1.063 | [6-(4-chloro-phenyl)-p...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26976PPUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM475791((1-cyclopropylmethoxy-isoquinolin-3-yl)- [(3aR,3bS...)copy SMILES
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26976PPUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477058(US10882857, Example 2.06 | US11673888, Example 2.0...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477062(US10882857, Example 4 | US11673888, Example 4 | [3...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442717(BDBM442732 | US10647719, Example 1.28 | [3-(2,2-di...)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511520(US11059794, Example 2.00 | US11059794, Example 2.0...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM475786((4-isopropoxy-naphthalen-2-yl)- [(3aR,3bS,6aR,6bS)...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26976PPUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511550(US11059794, Example 6.12 | tert-butyl 3-(2-fluoro-...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511540(US11059794, Example 6.02 | tert-butyl 4-(2,3-diflu...)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442702(US10647719, Example 1.13 | [5-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442707(US10647719, Example 1.18 | [6-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511559(US11059794, Example 6.19 | tert-butyl 4-(2-fluoro-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511557(US11059794, Example 6.17 | tert-butyl 4-[2-(2-fluo...)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511548(US11059794, Example 6.10 | tert-butyl 3-(2-fluoro-...)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477049(US10882857, Example 1.01 | US11673888, Example 1.0...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477042(US10882857, Example 1 | US11673888, Example 1 | [2...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM477060(US10882857, Example 3.01 | US11673888, Example 3.0...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9P52
TargetAtaxin-1(Homo sapiens (Human))TBA
LigandPNGBDBM511525(2-fluoro-4-sulfamoylbenzoic acid (CAS-RN 714968-42...)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K51US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442709(US10647719, Example 1.20 | [6-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 2nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM442711(US10647719, Example 1.22 | [6-chloro-3-(2,2-)copy SMILES
Affinity DataIC50: 2nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM442725(4-[2-[2-[4-cyano-2-[(5-methyl- | US10647719, Examp...)copy SMILES
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98C4VUS Patent
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