Compile Data Set for Download or QSAR
Found 26 with Last Name = 'dolan' and Initial = 'p'
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]1,25-dihydroxyvitamin D3 from human VDR by HAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9QS7PubMedDrugBank
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMedDrugBank
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411322copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411322copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200180(CHEMBL376093 | KSP-BCS-1-alpha-CHF2-20-epi-22-oxab...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]1,25-dihydroxyvitamin D3 from human VDR by HAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9QS7PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411326(CHEMBL2092724)copy SMILEScopy InChI
Affinity DataIC50: 20.5nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411324copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50158486((1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-4-(benzen...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200179((1S,3S,Z)-3-(difluoromethyl)-5-((E)-2-((1R,3aS,7aR...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]1,25-dihydroxyvitamin D3 from human VDR by HAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9QS7PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411324copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50224338((1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(4,4-dim...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200181(CHEMBL220140 | KSP-BCS-1-alpha-CHF2-1624F2-2)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]1,25-dihydroxyvitamin D3 from human VDR by HAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9QS7PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50411323(CHEMBL2093103)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50224334((1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(benzylo...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370926(CHEMBL1627204)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50224337((1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(3,3-dim...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50224332((1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-7a-methyl-1-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50224335((1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(2-(6,6-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of 1alpha, 25-(OH)[3H]D3 from human VDR expressed in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3DSSPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 312nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370927(CHEMBL1627205 | CHEMBL1627234)copy SMILEScopy InChI
Affinity DataIC50: 549nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)copy SMILEScopy InChI
Affinity DataIC50: 554nMAssay Description:Inhibition of human CYP27B hydroxylase expressed in SW900 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370932(CHEMBL1627208)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP27A1 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50370927(CHEMBL1627205 | CHEMBL1627234)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MRZPubMed