Compile Data Set for Download or QSAR
Found 91 with Last Name = 'goyal' and Initial = 'p'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281170(CHEMBL4165923 | US20240034730, Compound 2)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235594(CHEMBL4105330)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235596(CHEMBL4098306)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235589(CHEMBL4090575)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235597(CHEMBL4088968)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281172(CHEMBL4165815 | US20240034730, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235595(CHEMBL4081077)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50235593(CHEMBL4062046)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235593(CHEMBL4062046)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Turin

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2SPSPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235590(CHEMBL4071260)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462395(CHEMBL4238437)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50363559(CHEMBL1946659)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50509974(CHEMBL4434843)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C3 His5Gln mutant expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2SPSPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462394(CHEMBL4249650)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)copy SMILEScopy InChI
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)copy SMILEScopy InChI
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462391(CHEMBL4238142)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281168(CHEMBL4167855 | US20240034730, Compound 27)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462397(CHEMBL4245231)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50363564(CHEMBL1946851)copy SMILEScopy InChI
Affinity DataIC50: 599nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281167(CHEMBL4175712 | US20240034730, Compound 38)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235592(CHEMBL4061824)copy SMILEScopy InChI
Affinity DataIC50: 853nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50509973(CHEMBL4590005)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C3 His5Gln mutant expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2SPSPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462393(CHEMBL4249427)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507739(CHEMBL4458056)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462396(CHEMBL4238730)copy SMILEScopy InChI
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462394(CHEMBL4249650)copy SMILEScopy InChI
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462397(CHEMBL4245231)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281173(CHEMBL4169359)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507740(CHEMBL4539458)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WCQPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50462393(CHEMBL4249427)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VMTPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235591(CHEMBL4089886)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD215FPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C3 His5Gln mutant expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as r...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.97E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as reduction in NAD...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507745(CHEMBL4517934)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50509973(CHEMBL4590005)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C2 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as reduction in NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2SPSPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507737(CHEMBL4514989)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WCQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507736(CHEMBL4457827)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WCQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507738(CHEMBL4451149)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1WCQPubMed
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