Compile Data Set for Download or QSAR
Found 29 with Last Name = 'hatsis' and Initial = 'p'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502595(CHEMBL4554065)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502590(CHEMBL4434994)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502586(LCQ-908-NXA | LCQ-908NXA | LCQ908-NXA | Pradigasta...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502585(CHEMBL4446248)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502591(CHEMBL4563171)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502589(CHEMBL4540189)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502592(CHEMBL4555623)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502587(CHEMBL4463125)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502588(CHEMBL4439533)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502594(CHEMBL4475779)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491627(CHEMBL2386145)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491626(CHEMBL2386155)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491625(CHEMBL2386153)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491624(CHEMBL2386149)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491623(CHEMBL2386150)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491622(CHEMBL2386156)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491620(CHEMBL2386141)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491621(CHEMBL2386140)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QWDPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502589(CHEMBL4540189)copy SMILEScopy InChI
Affinity DataEC50:  27nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502593(CHEMBL4578901)copy SMILEScopy InChI
Affinity DataEC50:  8nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502594(CHEMBL4475779)copy SMILEScopy InChI
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502587(CHEMBL4463125)copy SMILEScopy InChI
Affinity DataEC50:  56nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502585(CHEMBL4446248)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502588(CHEMBL4439533)copy SMILEScopy InChI
Affinity DataEC50:  206nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502590(CHEMBL4434994)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502592(CHEMBL4555623)copy SMILEScopy InChI
Affinity DataEC50:  98nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502595(CHEMBL4554065)copy SMILEScopy InChI
Affinity DataEC50:  8nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502591(CHEMBL4563171)copy SMILEScopy InChI
Affinity DataEC50:  413nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502586(LCQ-908-NXA | LCQ-908NXA | LCQ908-NXA | Pradigasta...)copy SMILEScopy InChI
Affinity DataEC50:  71nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HJKPubMed