Compile Data Set for Download or QSAR
Found 69 with Last Name = 'hobza' and Initial = 'p'
TargetSerine racemase(Mus musculus)
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038343(CHEMBL3360546)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of mouse serine racemase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N53WKPubMed
TargetSerine racemase(Mus musculus)
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)copy SMILEScopy InChI
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of mouse serine racemase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N53WKPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16313(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamothioy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233206(CHEMBL4059895)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233212(CHEMBL4076762)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233207(CHEMBL4098319)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233211(CHEMBL4103466)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233213(CHEMBL4103343)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233966(CHEMBL4080296)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233965(CHEMBL4093993)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233967(CHEMBL4060905)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50029207((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233214(CHEMBL4086951)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233960(CHEMBL4102397)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233319(CHEMBL4094653)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104024(MK315)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 430nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200222(2-(2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 450nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233963(CHEMBL4096185)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B1 [L301M](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 710nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 710nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104021(MK408)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104025(MK409)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104023(MK257)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed at 25 degrees Celsius in a 100mM sodium phosphate buffer (pH 7.0), with the AR protein amount reaching the Vmax and 0.2mM N...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233210(CHEMBL4082771)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233208(CHEMBL4069574)copy SMILEScopy InChI
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50012899((Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233973(CHEMBL4104651)copy SMILEScopy InChI
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233970(CHEMBL4079098)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50233910(CHEMBL4074134)copy SMILEScopy InChI
Affinity DataIC50: 4.91E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C70PTPubMed
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