Affinity DataKi: 0.170nMAssay Description:Evaluated for binding activity against [3H]ketanserin as radioligand for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Compound was evaluated for binding activity against [3H]pyrilamine as radioligand for Histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Compound was evaluated for binding activity against [3H]-WB- 4101 as radioligand for alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 164nMAssay Description:Compound was evaluated for binding activity against [3H]-haloperidol as radioligand for Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 4.42E+3nMAssay Description:Compound was evaluated for binding activity against [3H]haloperidol as radioligand for Dopamine receptor D2More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.562nMAssay Description:Evaluated for binding activity against [3H]ketanserin as radioligand for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Compound was evaluated for binding activity against [3H]pyrilamine as radioligand for Histamine H1 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for binding activity against [3H]pyrilamine as radioligand for Histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Centre de Recherches de Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair