Compile Data Set for Download or QSAR
Found 215 with Last Name = 'limpachayaporn' and Initial = 'p'
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434076(CHEMBL2381343)copy SMILEScopy InChI
Affinity DataIC50: 0.951nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031605(CHEMBL3359197)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031610(CHEMBL3359202)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031602(CHEMBL3359194)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031608(CHEMBL3359200)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431505(CHEMBL2348701)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant caspase 3 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50257248((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031604(CHEMBL3359196)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431517(CHEMBL2348860)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50257249((S)-1-Butyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031610(CHEMBL3359202)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431504(CHEMBL2348702)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431513(CHEMBL2348693)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434076(CHEMBL2381343)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431509(CHEMBL2348697)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031594(CHEMBL3359186)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031603(CHEMBL3359195)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031592(CHEMBL3359184)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031595(CHEMBL3359187)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031605(CHEMBL3359197)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434074(CHEMBL2381345)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431514(CHEMBL2348692)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434077(CHEMBL2381348)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431508(CHEMBL2348698)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant caspase 3 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031601(CHEMBL3359193)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434074(CHEMBL2381345)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50257355((S)-1-(4-Fluorobutyl)-5-[1-(2-methoxymethylpyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50257249((S)-1-Butyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031604(CHEMBL3359196)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031597(CHEMBL3359189)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431510(CHEMBL2348696)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031611(CHEMBL3359203)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431505(CHEMBL2348701)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031611(CHEMBL3359203)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50257355((S)-1-(4-Fluorobutyl)-5-[1-(2-methoxymethylpyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031593(CHEMBL3359185)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50431517(CHEMBL2348860)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant caspase 3 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T5HPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031602(CHEMBL3359194)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031596(CHEMBL3359188)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50434073(CHEMBL2381346)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54N5PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50031608(CHEMBL3359200)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
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