Compile Data Set for Download or QSAR
Found 147 with Last Name = 'manjrekar' and Initial = 'p'
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123118((S)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123125((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123114((1R,2S)-1-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123127((R)-((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123107((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123123((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123124((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123111((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123119((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123124((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123114((1R,2S)-1-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123122((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123125((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123122((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123118((S)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123117((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123123((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123108(((S)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123127((R)-((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123111((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123121((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 6nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123113((S)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123126((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123120((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123112((S)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123105((S)-2-(4-(5-tert-butyl-1H-pyrazol-3-ylamino)-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123115((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123116((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123106((R)-2-cyclohexyl-2-(4-(3-isopropyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123104((S)-2-cyclohexyl-2-(4-(5-isopropyl-1H-pyrazol-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123112((S)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123109(2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123110((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123119((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123117((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 21nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123115((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 40nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123103((S)-2-cyclohexyl-2-(4-(3-cyclopropyl-1H-pyrazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123121((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 52nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123120((R)-2-((4-((5-(tert-butyl)-1-methyl-1H-pyrazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 57nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123126((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123113((S)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123109(2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 101nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123110((R)-2-(4-(5-tert-butyl-1-methyl-1H-pyrazol-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 188nMT: 2°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50020412(CHEMBL3289811)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3501CPubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (G-proteobacteria))
AstraZeneca India Pvt. Ltd.

LigandPNGBDBM123102((1-(4-(3-cyclopropyl-1H-pyrazol-5-ylamino)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6Q7XPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50054813(CHEMBL3318989)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5BMKPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50020412(CHEMBL3289811)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3501CPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50018442(CHEMBL3286436)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiological analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZM4PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50020404(CHEMBL3289803)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3501CPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50020413(CHEMBL3289807)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3501CPubMed
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