Compile Data Set for Download or QSAR
Found 105 with Last Name = 'perego' and Initial = 'p'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399922(CHEMBL2180974)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399922(CHEMBL2180974)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399923(CHEMBL2180979)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399919(CHEMBL2180983)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50177879(CHEMBL200182 | ST-1646)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401475(CHEMBL2205248)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399918(CHEMBL2180982)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401483(CHEMBL2204574)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50177879(CHEMBL200182 | ST-1646)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta5 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401484(CHEMBL2204575)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401493(CHEMBL2205246)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401477(CHEMBL2204567)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401489(CHEMBL2204580)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401481(CHEMBL2204572)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401485(CHEMBL2204576)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401492(CHEMBL2204582)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399912(CHEMBL2180973)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401488(CHEMBL2204579)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401474(CHEMBL2205247)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401482(CHEMBL2204573)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401487(CHEMBL2204578)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399915(CHEMBL2180976)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401479(CHEMBL2204569)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401480(CHEMBL2204571)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401488(CHEMBL2204579)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401487(CHEMBL2204578)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399924(CHEMBL2180975)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401483(CHEMBL2204574)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399916(CHEMBL2180980)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401476(CHEMBL2205249)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399914(CHEMBL2180977)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401478(CHEMBL2204568)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399920(CHEMBL2180984)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401490(CHEMBL2204570)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401491(CHEMBL2204581)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401484(CHEMBL2204575)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta5 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399913(CHEMBL2180978)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401482(CHEMBL2204573)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399921(CHEMBL2180985)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta3 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401480(CHEMBL2204571)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401485(CHEMBL2204576)copy SMILEScopy InChI
Affinity DataIC50: 15.5nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401481(CHEMBL2204572)copy SMILEScopy InChI
Affinity DataIC50: 15.5nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401486(CHEMBL2204577)copy SMILEScopy InChI
Affinity DataIC50: 16.2nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401476(CHEMBL2205249)copy SMILEScopy InChI
Affinity DataIC50: 17.6nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Universit£ degli Studi di Milano

Curated by ChEMBL
LigandPNGBDBM50399918(CHEMBL2180982)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Competitive inhibition of biotinylated vitronectin to integrin alphaVbeta5 receptor after 3 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41Q5PubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione IRCCS Istituto Nazionale dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401475(CHEMBL2205248)copy SMILEScopy InChI
Affinity DataIC50: 24.5nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84D2ZPubMed
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