Compile Data Set for Download or QSAR
Found 152 with Last Name = 'tosco' and Initial = 'p'
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426821(4-(2-Guanidinoethyl)Benzenesulfonamide Hydrochlori...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426821(4-(2-Guanidinoethyl)Benzenesulfonamide Hydrochlori...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426821(4-(2-Guanidinoethyl)Benzenesulfonamide Hydrochlori...)copy SMILEScopy InChI
Affinity DataKi:  89nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426821(4-(2-Guanidinoethyl)Benzenesulfonamide Hydrochlori...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50014341(4-amino(immino)methylaminobenzoate)copy SMILEScopy InChI
Affinity DataKi:  480nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50014341(4-amino(immino)methylaminobenzoate)copy SMILEScopy InChI
Affinity DataKi:  630nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50014341(4-amino(immino)methylaminobenzoate)copy SMILEScopy InChI
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50014341(4-amino(immino)methylaminobenzoate)copy SMILEScopy InChI
Affinity DataKi:  2.56E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426822(1-(4-Hydroxyphenyl)Guanidine Hydrochloride | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  4.13E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426822(1-(4-Hydroxyphenyl)Guanidine Hydrochloride | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  7.51E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426822(1-(4-Hydroxyphenyl)Guanidine Hydrochloride | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  8.34E+3nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)copy SMILEScopy InChI
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)copy SMILEScopy InChI
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26187(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)copy SMILEScopy InChI
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50426822(1-(4-Hydroxyphenyl)Guanidine Hydrochloride | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  1.46E+4nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q16PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187442(1-(6-bromo-5-(vinyloxy)pyridin-3-yl)-1,5-diazocane...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187445(1-(6-bromopyridin-3-yl)-1,5-diazocane | 1-(6-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 0.447nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187455(1-(6-Bromo-5-vinylpyridin-3-yl)-[1,4]diazepane | 1...)copy SMILEScopy InChI
Affinity DataIC50: 0.646nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088456(1-(6-Chloro-5-methoxy-pyridin-3-yl)-[1,4]diazepane...)copy SMILEScopy InChI
Affinity DataIC50: 0.676nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088453(1-(6-Bromo-5-ethoxy-pyridin-3-yl)-[1,4]diazepane |...)copy SMILEScopy InChI
Affinity DataIC50: 0.871nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187447(1-(pyridin-3-yl)-1,5-diazocane | 1-pyridin-3-yl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 0.891nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088454(1-(6-Bromo-pyridin-3-yl)-[1,4]diazepane | 1-(6-bro...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187439(1-(5-Methoxypyridin-3-yl)-[1,5]diazocane | 1-(5-me...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187438((Z)-1-(5-(prop-1-enyloxy)pyridin-3-yl)-1,4-diazepa...)copy SMILEScopy InChI
Affinity DataIC50: 1.29nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187453(1-(6-bromo-5-chloropyridin-3-yl)-1,4-diazepane | 1...)copy SMILEScopy InChI
Affinity DataIC50: 1.41nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187441(1-(5-bromo-6-chloropyridin-3-yl)-1,4-diazepane | 4...)copy SMILEScopy InChI
Affinity DataIC50: 1.41nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50049750((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...)copy SMILEScopy InChI
Affinity DataIC50: 1.51nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088457(1-(5-Methoxy-pyridin-3-yl)-[1,4]diazepane | 1-(5-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.91nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088438(1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 1.91nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187437(1-(5-chloropyridin-3-yl)-1,5-diazocane | 1-(5-chlo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088443(1-(5-(2-methoxyethoxy)pyridin-3-yl)-1,4-diazepane ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088448(5-(1,4-diazepan-1-yl)pyridin-3-ol | 5-[1,4]Diazepa...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187454(1-(5-Bromopyridin-3-yl)-[1,5]diazocane | 1-(5-brom...)copy SMILEScopy InChI
Affinity DataIC50: 2.82nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088451(3-(5-Methoxy-pyridin-3-yl)-9-aza-bicyclo[3.3.1]non...)copy SMILEScopy InChI
Affinity DataIC50: 3.02nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088452(3-(pyridin-3-yl)-9-azabicyclo[3.3.1]non-2-ene | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.47nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088450(1-(5-(vinyloxy)pyridin-3-yl)-1,4-diazepane | 1-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50413479(CHEMBL500726)copy SMILEScopy InChI
Affinity DataIC50: 6.61nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088458(3-(pyridin-3-yl)-8-azabicyclo[3.2.1]oct-3-ene | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 6.76nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088432(5-(1,4-diazepan-1-yl)nicotinamide | 5-[1,4]Diazepa...)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£ di Torino

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£ di Torino

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187459(5-(1,4-diazepan-1-yl)-2-iodopyridin-3-ol | 5-[1,4]...)copy SMILEScopy InChI
Affinity DataIC50: 21.9nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GS0PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£ di Torino

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£ di Torino

Curated by ChEMBL
LigandPNGBDBM50363564(CHEMBL1946851)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995NCPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£ di Torino

Curated by ChEMBL
LigandPNGBDBM50363559(CHEMBL1946659)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995NCPubMed
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