Compile Data Set for Download or QSAR
Found 501 with Last Name = 'toy' and Initial = 'p'
TargetSerine/threonine-protein kinase TNNI3K(Homo sapiens (Human))TBA
LigandPNGBDBM50578225(CHEMBL4869303)copy SMILES
Affinity DataKi:  0.540nMAssay Description:Binding affinity to full length human His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
LigandPNGBDBM50578225(CHEMBL4869303)copy SMILES
Affinity DataKi:  13nMAssay Description:Binding affinity to full length mouse His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141580(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)copy SMILEScopy InChI
Affinity DataIC50: 0.117nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)copy SMILEScopy InChI
Affinity DataIC50: 0.171nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)copy SMILEScopy InChI
Affinity DataIC50: 0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)copy SMILEScopy InChI
Affinity DataIC50: 0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)copy SMILEScopy InChI
Affinity DataIC50: 0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104208(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141584(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578208(CHEMBL4875220)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141588(4-(3-Chloro-4-methoxy-benzylamino)-3-hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502628(CHEMBL4469630)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)copy SMILEScopy InChI
Affinity DataIC50: 0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141586(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141583(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104206(5-(3-Chloro-4-methoxy-benzylamino)-8-[5-((R)-3-dim...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50450513(CHEMBL4168219)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8H2PPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502635(CHEMBL4521512)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502648(CHEMBL4588831)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578207(CHEMBL4845883)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50554960(CHEMBL4749555)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK or HEK MSR2 cells assessed as inhibition of TRPV4 agonist GSK634775 (EC80)-induced response incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PFKPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141587(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141582(4-(3-Chloro-4-methoxy-benzylamino)-quinoline-6-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502626(CHEMBL4536058)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502640(CHEMBL4470585)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of rat TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502649(CHEMBL4532369)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S78PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104204(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502643(CHEMBL4541827)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502640(CHEMBL4470585)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578189(CHEMBL4856992)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104207(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1BM5PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50450500(CHEMBL4164465)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8H2PPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578219(CHEMBL4857556)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502653(CHEMBL4514491)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50450500(CHEMBL4164465)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8H2PPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM68211(Type II inhibitor, 5)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502636(CHEMBL4588158)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578209(CHEMBL4867760)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578191(CHEMBL4852364)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578183(CHEMBL1992306)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141579(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50502637(CHEMBL4469982)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GBFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578186(CHEMBL4870490)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50578221(CHEMBL4870768)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetProgesterone receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304973((S)-4-((2-bromobenzyl)(1-(methylsulfonyl)pyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057G17PubMed
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