Compile Data Set for Download or QSAR
Found 377 with Last Name = 'blomgren' and Initial = 'pa'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111938(US8618107, 104)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111940(US8618107, 106)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111953(US8618107, 212)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111975(US8618107, 287)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111978(US8618107, 291)copy SMILEScopy InChI
Affinity DataIC50: 1.74nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111935(US8618107, 101)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111949(US8618107, 131)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111951(US8618107, 197)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111956(US8618107, 268)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111976(US8618107, 288)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111982(US8618107, 295)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111964(US8618107, 276)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111962(US8618107, 274)copy SMILEScopy InChI
Affinity DataIC50: 2.34nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111966(US8618107, 278)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111972(US8618107, 284)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111954(US8618107, 265)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111948(US8618107, 123)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111983(US8618107, 296)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111994(US8618107, 308)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111987(US8618107, 300)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111965(US8618107, 277)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111974(US8618107, 286)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111973(US8618107, 285)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111955(US8618107, 267)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111952(US8618107, 210)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111958(US8618107, 270)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111957(US8618107, 269)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111970(US8618107, 282)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111984(US8618107, 297)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111968(US8618107, 280)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111959(US8618107, 271)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111990(US8618107, 303)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111967(US8618107, 279)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111977(US8618107, 289)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111950(US8618107, 149)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111945(US8618107, 113)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111997(US8618107, 311)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111969(US8618107, 281)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111985(US8618107, 298)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111946(US8618107, 116)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111988(US8618107, 301)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111942(US8618107, 108)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K076M3US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49T3HUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111943(US8618107, 109)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMpH: 7.0 T: 2°CAssay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TB7US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMpH: 7.0Assay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15RTUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD22RGUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
University of Wisconsin-Milwaukee

LigandPNGBDBM212270(6-(6-amino-5-methylpyrazin-2-yl)-N-(4-(4-(oxetan-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Syk activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, Syk-ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0K6DUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Gilead Connecticut, Inc.; Genentech, Inc.

US Patent
LigandPNGBDBM111961(US8618107, 273)copy SMILEScopy InChI
Affinity DataIC50: 6.35nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds. Alternatively, the Lanthascreen ass...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72G3CUS Patent
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