TargetSubstance-P receptor(Rattus norvegicus (rat))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]GR205171 from Mongolian gerbil brain NK1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.0813nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.117nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR205171 from human NK1 receptor in cortex homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.138nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.275nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.437nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.537nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.646nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1.29nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 3.72nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 8.13nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 8.71nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 18.2nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Inhibition of sigma1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2.27E+3nMAssay Description:Inhibition of platelet activating factor receptor (unknown origin)More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2.98E+3nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.610nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataKd: 0.0302nMAssay Description:Binding affinity to human recombinant NK1 receptor expressed in CHO cells assessed as dissociation constantMore data for this Ligand-Target Pair