Compile Data Set for Download or QSAR
Found 46 with Last Name = 'gerrard' and Initial = 'pa'
TargetSubstance-P receptor(Rattus norvegicus (rat))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442585(GW823296X | ORVEPITANT)copy SMILEScopy InChI
Affinity DataKi:  0.0316nMAssay Description:Displacement of [3H]GR205171 from Mongolian gerbil brain NK1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50408664(GR-205171 | VOFOPITANT)copy SMILEScopy InChI
Affinity DataKi:  0.0501nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442585(GW823296X | ORVEPITANT)copy SMILEScopy InChI
Affinity DataKi:  0.0631nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442588(CHEMBL2441373)copy SMILEScopy InChI
Affinity DataKi:  0.0646nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417977(CHEMBL1672044)copy SMILEScopy InChI
Affinity DataKi:  0.0794nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417978(CHEMBL1672047)copy SMILEScopy InChI
Affinity DataKi:  0.0813nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417973(CHEMBL1672053)copy SMILEScopy InChI
Affinity DataKi:  0.117nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)copy SMILEScopy InChI
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]GR205171 from human NK1 receptor in cortex homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442589(CHEMBL2441371)copy SMILEScopy InChI
Affinity DataKi:  0.138nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417972(CHEMBL1672051)copy SMILEScopy InChI
Affinity DataKi:  0.141nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417982(CHEMBL1672058)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417970(CHEMBL1672048)copy SMILEScopy InChI
Affinity DataKi:  0.178nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417974(CHEMBL1672056)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417980(CHEMBL1672052)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442590(CHEMBL2441372)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417976(CHEMBL1672059)copy SMILEScopy InChI
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413891(VESTIPITANT)copy SMILEScopy InChI
Affinity DataKi:  0.224nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413891(VESTIPITANT)copy SMILEScopy InChI
Affinity DataKi:  0.224nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417968(CHEMBL1672045)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417979(CHEMBL1672050)copy SMILEScopy InChI
Affinity DataKi:  0.275nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417975(CHEMBL1672057)copy SMILEScopy InChI
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)copy SMILEScopy InChI
Affinity DataKi:  0.331nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413892(CHEMBL490926)copy SMILEScopy InChI
Affinity DataKi:  0.427nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417981(CHEMBL1672055)copy SMILEScopy InChI
Affinity DataKi:  0.437nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413890(CHEMBL492117 | TCMDC-138495)copy SMILEScopy InChI
Affinity DataKi:  0.537nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417971(CHEMBL1672049)copy SMILEScopy InChI
Affinity DataKi:  0.646nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50417969(CHEMBL1672046)copy SMILEScopy InChI
Affinity DataKi:  0.933nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413892(CHEMBL490926)copy SMILEScopy InChI
Affinity DataKi:  1.29nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413888(CHEMBL523156)copy SMILEScopy InChI
Affinity DataKi:  3.72nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413889(CHEMBL489924)copy SMILEScopy InChI
Affinity DataKi:  8.13nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413894(CHEMBL521605)copy SMILEScopy InChI
Affinity DataKi:  8.71nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413893(CHEMBL522292)copy SMILEScopy InChI
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442585(GW823296X | ORVEPITANT)copy SMILEScopy InChI
Affinity DataKi:  940nMAssay Description:Inhibition of sigma1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442585(GW823296X | ORVEPITANT)copy SMILEScopy InChI
Affinity DataKi:  2.27E+3nMAssay Description:Inhibition of platelet activating factor receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50336575(CHEMBL1672054 | cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(...)copy SMILEScopy InChI
Affinity DataKi:  2.98E+3nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M1XPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442587(CHEMBL2441370)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50185071((5S,6S,7S)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMedDrugBank
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50442586(CHEMBL2441368)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50029884((2S,3S)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413891(VESTIPITANT)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50408458(CHEMBL340559)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50178574(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CWCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413891(VESTIPITANT)copy SMILEScopy InChI
Affinity DataKd:  0.0302nMAssay Description:Binding affinity to human recombinant NK1 receptor expressed in CHO cells assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP0425PubMed