Compile Data Set for Download or QSAR
Found 520 with Last Name = 'skone' and Initial = 'pa'
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50354851(FLUTICASONE FUROATE | Veramyst)copy SMILEScopy InChI
Affinity DataIC50: 0.0398nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414604(CHEMBL551816)copy SMILEScopy InChI
Affinity DataIC50: 0.0790nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414609(CHEMBL550730)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414610(CHEMBL564160)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414607(CHEMBL563812)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414611(CHEMBL560797)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414605(CHEMBL556231)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414612(CHEMBL559115)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414608(CHEMBL550933)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414613(CHEMBL561475)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414615(CHEMBL559942)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414606(CHEMBL550258)copy SMILEScopy InChI
Affinity DataIC50: 0.501nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414618(CHEMBL563595)copy SMILEScopy InChI
Affinity DataIC50: 0.794nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414614(CHEMBL561276)copy SMILEScopy InChI
Affinity DataIC50: 0.794nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.17nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411047(CHEMBL211441)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411047(CHEMBL211441)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414623(CHEMBL394168)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411480(CHEMBL398572)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414623(CHEMBL394168)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411489(CHEMBL238147)copy SMILEScopy InChI
Affinity DataIC50: 1.95nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411024(CHEMBL208996)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411024(CHEMBL208996)copy SMILEScopy InChI
Affinity DataIC50: 2.04nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411487(CHEMBL236229)copy SMILEScopy InChI
Affinity DataIC50: 2.19nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411487(CHEMBL236229)copy SMILEScopy InChI
Affinity DataIC50: 2.19nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414619(CHEMBL559547)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423192(CHEMBL237973)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423192(CHEMBL237973)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411026(CHEMBL214336)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411477(CHEMBL393551)copy SMILEScopy InChI
Affinity DataIC50: 3.09nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411039(CHEMBL385450)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50414616(CHEMBL558716)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Agonist activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20HHPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411034(CHEMBL378785)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411034(CHEMBL378785)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50254466(5-amino-N-(2-((2,6-dichloro-N-ethylbenzamido)methy...)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411036(CHEMBL383890)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411020(CHEMBL211266)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411488(CHEMBL236018)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411488(CHEMBL236018)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RRRPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419265(CHEMBL1835069)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423195(CHEMBL393011)copy SMILEScopy InChI
Affinity DataIC50: 4.47nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423195(CHEMBL393011)copy SMILEScopy InChI
Affinity DataIC50: 4.47nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 4.68nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells transfected with MMTV luciferase reporter gene assessed as inhibition of dexametha...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423195(CHEMBL393011)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411048(CHEMBL386448)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50411037(CHEMBL213453)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC40SBPubMed
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